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Small bowel distension is mandatory for the assessment of the bowel wall in CT enterography, but some patients were sufferring inadequate small bowel distension. So, it is important to prescribe personalized regimen according to patient's personal characteristics.
CT enterography has become an important tool in the evaluation of small bowel diseases, especially in patients with inflammatory bowel diseases. Small bowel distension is mandatory for the assessment of the bowel wall. So, it is important to find clinical risk factors for inadequate small bowel distension and prescribe personalized regimen according to patient's personal characteristics to reduce patient acceptance.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Individualized group | Active Comparator | Participants are given different volume of a preparation of mannitol based on BMI as oral contrast agent over an hour prior to the examination. |
|
| conventional group | Experimental | Participants are given 1500ml of a preparation of mannitol as oral contrast agent over an hour prior to the examination. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| 1500ml of 2.5% mannitol | Drug | 1500ml of 2.5% mannitol was used in experimental group |
|
| Measure | Description | Time Frame |
|---|---|---|
| Clinical risk factors for inadequate small bowel distention | Number of clinical risk factors for inadequate small bowel distention | 2 month |
| Adequate small bowel distention | The assessment system includes four parts
| 4 month |
| Measure | Description | Time Frame |
|---|---|---|
| Side effects | Side effects in 2 groups The degree of nausea, emesis, diarrhea, abdominal distension and cramp following ingestion are scored on a scale ranging from 0 to 4, in which a higher score represents a higher level of these targets. | 4 month |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yanqing Li, PhD, MD | Contact | 86-531-82169236 | liyanqing@sdu.edu.cn |
| Name | Affiliation | Role |
|---|---|---|
| Yanqing Li, PhD, MD | Qilu Hospital of Shandong University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Gastroenterology, Qilu Hospital, Shandong University | Jinan | Shandong | 250012 | China |
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| ID | Term |
|---|---|
| D008353 | Mannitol |
| ID | Term |
|---|---|
| D013402 | Sugar Alcohols |
| D000438 | Alcohols |
| D009930 | Organic Chemicals |
| D002241 | Carbohydrates |
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| different volume of 2.5% mannitol | Drug | different volume of 2.5% mannitol based on BMI was used in active comparator group |
|