A Postoperative Sore Throat After Thyroidectomy | NCT03805568 | Trialant

A Postoperative Sore Throat After Thyroidectomy | NCT03805568 | Trialant

Arms/Interventions Module

Arm Groups

Label	Type	Description	Intervention Names
dexmedetomidine infusion group	Active Comparator	dexmedetomidine infusion (loading dose of 1 ㎍/kg over 10 min and continuous infusion of 0.3-0.6 ㎍/kg/h) during the surgery	Drug: dexmedetomidine infusion group
remifentanil infusion group	Active Comparator	remifentanil of 4 ng/ml during induction, followed by remifentanil infusion (1.5~2.5 ng/ml) during the surgery	Drug: remifentanil infusion group

Outcomes Module

Primary Outcomes

Measure	Description	Time Frame
incidence of postoperative sore throat at rest	0=none; 1=occur	6 hours after surgery
incidence of postoperative sore throat at swallowing	0=none; 1=occur	6 hours after surgery
severity of postoperative sore throat at rest	4-point scale (0=none; 1=mild; 2=moderate; 3=severe)	6 hours after surgery
severity of postoperative sore throat at swallowing	4-point scale (0=none; 1=mild; 2=moderate; 3=severe)	6 hours after surgery