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The primary object of this study is, to investigate the current procedure of neuromuscular monitoring at a tertiary academic university medical center.
Residual neuromuscular block is known to be a significant but frequently overlooked complication after the use of neuromuscular blocking agents. Aim of this prospective, observational study is to detect the incidence and severity of residual paralysis at a tertiary academic german university medical center.
Methods:
All infantile patients recieving neuromuscular blocking agents are included over a 12 week observational period. At the end of the operation procedure, directly prior to tracheal extubation a train-of-four ratio was assessed quantitatively by an independet observer using the TOF Watch SX monitor. Data related to patient postoperative outcome were collected in the operating theatre, during the way to the postoperative care unit (PACU) and during the stay in the PACU:
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Acceleromyography | Diagnostic Test | At the End of Surgery, shortly before Extubation, the TOF-Ratio is measured by an independent investigator using Acceleromyography. |
| Measure | Description | Time Frame |
|---|---|---|
| Residual paralysis | Rate of residual paralysis after extubation of the infantile patients measured by acceleromyography. | Directly prior to extubation |
| Measure | Description | Time Frame |
|---|---|---|
| Airway obstruction | Clinical assessment of the upper airway | 1, 10, 30, 60 minutes after extubation |
| Oxygen desaturation | Measurement of the oxygen saturation by pulse oxymetry |
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Inclusion Criteria:
Exclusion Criteria:
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All children/youths between 1 Month to 18 years who are undergoing general anaesthesia with muscle relaxation due to surgical or diagnostical procedures.
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| Name | Affiliation | Role |
|---|---|---|
| Christoph Unterbuchner, MD | University medical center Regensburg, Department of anaesthesiology | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| University Hospital Regensburg | Regensburg | Bavaria | 93053 | Germany |
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| ID | Term |
|---|---|
| D055191 | Delayed Emergence from Anesthesia |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| 1, 10, 30, 60 minutes after extubation |
| Bronchospasm, laryngospasm | Clinical assessment the airway | 1, 10, 30, 60 minutes after extubation |