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A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria were randomly assigned to the exercise group (n=32) or the control group (n=30).
Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises, of 30 minutes duration daily, for 12 weeks. Performance of daily activities was evaluated with the DASH and HAQ questionnaires, grip and pinch strength with the Jamar dynamometer and pinch gauge tools respectively, dexterity with the Purdue pegboard test and the quality of life with the LUPUSQoL questionnaire at 0, 6, 12 (end of the exercise program) and 24 weeks for both groups. SLE activity and cumulative organ damage were evaluated with the SLE disease activity index 2000 (SLEDAI-2K) and SLICC/ACR-DI, respectively.
A total of 240 consecutive SLE patients fulfilling the SLICC classification criteria was evaluated. Sixty two patients who met the inclusion criteria [age>18, upper limb arthralgias, and DASH (Disabilities of the Arm, Shoulder, and Hand) questionnaire score>10)] were randomly assigned to the exercise group (n=32) or the control group (n=30).
Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises, of 30 minutes duration daily, for 12 weeks. Performance of daily activities was evaluated with the DASH and HAQ questionnaires, grip and pinch strength with the Jamar dynamometer and pinch gauge tools respectively, dexterity with the Purdue pegboard test and the quality of life with the LUPUSQoL questionnaire at 0, 6, 12 (end of the exercise program) and 24 weeks for both groups. SLE activity and cumulative organ damage were evaluated with the SLE disease activity index 2000 (SLEDAI-2K) and SLICC/ACR-DI, respectively.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| EXERCISE GROUP | Experimental | Patients in the exercise group performed a program of strengthening, stretching and resistance upper limbs exercises (Hand exercise), of 30 minutes duration daily, for 12 weeks in addition to medical care. |
|
| CONTROL GROUP | No Intervention | Patients in the control group continued their usual medical care. |
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| HAND EXERCISE | Behavioral |
|
| Measure | Description | Time Frame |
|---|---|---|
| change of DASH questionnaire | Hand function was measured with DASH Questionnaire | Baseline, 6, 12, 24 weeks |
| Measure | Description | Time Frame |
|---|---|---|
| change of HAQ questionnaire | Hand function was measured with HAQ Questionnaire | Baseline, 6, 12, 24 weeks |
| change of Grip strength | Grip strength was measured with Jamar Dynamometer |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| MARIA TEKTONIDOU, Ass. Prof | National and Kapodistrian University of Athens | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| General Hospital of Athens 'Laiko' | Athens | Attica | 11527 | Greece | ||
| General Hospital of Elefsina 'Thriasio' |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31958285 | Derived | Keramiotou K, Anagnostou C, Kataxaki E, Galanos A, Sfikakis PP, Tektonidou MG. The impact of upper limb exercise on function, daily activities and quality of life in systemic lupus erythematosus: a pilot randomised controlled trial. RMD Open. 2020 Jan;6(1):e001141. doi: 10.1136/rmdopen-2019-001141. |
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| ID | Term |
|---|---|
| D008180 | Lupus Erythematosus, Systemic |
| D018771 | Arthralgia |
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D003240 | Connective Tissue Diseases |
| D017437 | Skin and Connective Tissue Diseases |
| D001327 | Autoimmune Diseases |
| D007154 | Immune System Diseases |
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| Baseline, 6, 12, 24 weeks |
| change of Pinch strength | Pinch strength was measured with Jamar pinch gauge | Baseline, 6, 12, 24 weeks |
| change of Dexterity | Dexterity was measured with Purdue Pegboard test | Baseline, 6, 12, 24 weeks |
| change of Quality of Life | Quality of Life was measured with LupusQoL Questionnaire | Baseline, 6, 12, 24 weeks |
| Elefsina |
| Attica |
| 19600 |
| Greece |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D001519 | Behavior |