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The investigators examined the effects on post-digestion brachial artery flow mediated dilation (FMD) and in vitro antioxidant capacity of 40% semolina flour replacement with sprouted chickpea flour.
The purpose of the current study was to examine in-vitro and in-vivo effects of replacing 40% of semolina flour with sprouted chickpea flour for the use in pasta. Antioxidant capacity in-vitro was measured by Trolox Equivalent Antioxidant Capacity. Brachial artery flow-mediated dilation, a test of in-vivo endothelial function, was performed for assessment of effects on post-digestion endothelial function. The investigators hypothesized that FMD would be higher after consuming 40% of semolina flour with sprouted chickpea flour pasta vs. 100% of semolina flour pasta.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Experimental (SCF40) | At the experimental data collection visits participants consumed 255g of pasta made with 40% sprouted chickpea flour and 60% semolina flour (SCF40) with butter. |
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| Control (SEM100) | At the control data collection visits participants consumed 255g of pasta made with 100% semolina flour (SEM100) with butter. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Experimental: Sprouted Chickpea Flour | Other | 255g of pasta with 40% sprouted chickpea flour and 60% semolina flour (SCF40) with butter. |
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| Measure | Description | Time Frame |
|---|---|---|
| Post-digestion flow mediated dilation | Post meal | Two hours following meal |
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Inclusion Criteria:
Exclusion Criteria:
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Healthy adults
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31564118 | Derived | Bruno JA, Feldman CH, Konas DW, Kerrihard AL, Matthews EL. Incorporating sprouted chickpea flour in pasta increases brachial artery flow-mediated dilation. Physiol Int. 2019 Sep 1;106(3):207-212. doi: 10.1556/2060.106.2019.21. Epub 2019 Sep 30. |
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| Control: Semolina Flour | Other | 255g of pasta with 100% semolina flour (SEM100) with butter. |
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