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| Name | Class |
|---|---|
| First Affiliated Hospital of Wenzhou Medical University | OTHER |
| Second Affiliated Hospital of Wenzhou Medical University | OTHER |
| Jinhua Central Hospital | OTHER |
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Aortic valve stenosis (AVS) is becoming more and more frequent with the aging, which has brought a heavy burden to the world. However, the prevalence and prognosis of valvular heart disease are not so clear, especially in the developing countries such as China etc. Because of the slow and progressive nature of AVS, symptoms might not be too severe to be diagnosed on time. Our retrospective survey (Int J Cardiol. 2016 Nov 25) indicated that severe aortic valve stenosis are very common in China. Hence, we design a prospective, observational cohort study to provide contemporary information on the prevalence, characteristics, risk stratification,cost-effective ,treatments and prognosis of Chinese elderly patients with aortic valve stenosis.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Our study type is observational | Other | Our study type is observational |
| Measure | Description | Time Frame |
|---|---|---|
| All-cause mortality,disabling strokes and Surgical or transcatheter aortic valve replacement | time from enrolled to first occurrence of any of the components of the composite outcome | one year |
| Measure | Description | Time Frame |
|---|---|---|
| Hospitalization for heart failure | time from enrolled to first occurrence of the outcome | one year |
| Surgical or transcatheter aortic valve replacement | time from enrolled to first occurrence of the outcome |
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Inclusion Criteria:
1. Patients over 60 years old meet the following condition moderate or above aortic stenosis as defined by echocardiography: Aortic stenosis, moderate or above, or valve area≤1.5cm2, or maximal jet velocity ≥3.0m/sec, or mean pressure gradient≥20mmHg
Exclusion Criteria:
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Patients over 60 years old and moderate or above aortic stenosis
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Second Affiliated Hospital Zhejiang University School of Medicine | Recruiting | Hangzhou | Zhejiang | 310000 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 27908608 | Background | Hu P, Liu XB, Liang J, Zhu QF, Pu CX, Tang MY, Wang JA. A hospital-based survey of patients with severe valvular heart disease in China. Int J Cardiol. 2017 Mar 15;231:244-247. doi: 10.1016/j.ijcard.2016.11.301. Epub 2016 Nov 25. |
| Label | URL |
|---|---|
| A hospital-based survey of patients with severe valvular heart disease in China | View source |
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| ID | Term |
|---|---|
| D006349 | Heart Valve Diseases |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| The Second Affiliated Hospital of Jiaxing University |
| OTHER |
| The Fourth Affiliated Hospital of Zhejiang University School of Medicine | OTHER |
| The Central Hospital of Lishui City | OTHER |
| Sir Run Run Shaw Hospital | OTHER |
| Ningbo Medical Center Lihuili Hospital | OTHER_GOV |
| Ningbo No. 1 Hospital | OTHER |
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| one year |
| Cardiovascular death | time from enrolled to first occurrence of the outcome | one year |