Does Myomectomy for Intramural Fibroid Improve ART Outcome?

Does Myomectomy for Intramural Fibroid Improve ART Outcome? A Randomized Controlled Trial

Intamural fibroids (myoma) do exist in some infertile women undergoing IVF treatment. There is controversy whether myomectomy before IVF treatment could improve IVF outcome. This trial will examine whether myomectomy in those patients could improve the results.

This study will include women who have intramural myoma ranging from 3-5 cm

The participants will be randomly allocated into two groups.

In group (1): myomectomy will be performed before ART

In group (2):women will have their trial of ART without myomectomy

In group A, ART will be performed 3 months after myomectomy if the uterine cavity is not opened and 6 months after myomectomy upon inadvertent opening of the uterine cavity during surgery

Inclusion Criteria:

• Inclusion criteria:
• Women with intramural fibroid without any cavity involvement
• Age ˂ 35 years
• I onCSI or IVF cycles
• normal uterine cavity

Exclusion Criteria:

• Exclusion criteria:
• low ovarian reserve (AFC < 7 and or AMH < 1.1 ng/ml)
• Endometrioma
• Untreated hydrosalpinx
• Non obstructive azoospermia
• Any other cavitary lesions (Asherman syndrome, Mullerian anomalies)
• recurrent implantation failure