Follow-up of Sequential Chemotherapy and Stimulation for Fertility Preservation in Young Patients With Breast Cancer

Long-term Follow-up of Sequential Chemotherapy and Stimulation for Fertility Preservation in Young Patients Treated for a Breast Cancer

Interventional research with low risks and constraints, prospective and monocentric on the assessment of long-term fertility in patients who underwent an adjuvant sequential chemotherapy with or without a controled ovarian hyperstimulation. This study follows a previous one called NCT 01614704.

The patients will have a follow-up once a year during ten years beginning at the end of their chemotherapy.

They will have a consultation in oncology consisting of:

• a clinical exam,
• a collection and follow-up of oncological data
• a collection of ongoing cancer treatments

and a consultation in gynecology consisting of:

• a pelvic ultrasound scan (for AFC: Antral Follicle Count)
• a biological test (FSH, LH, E2, AMH)
• a collection of gynecological data, contraception and reproductive medicine

Inclusion Criteria:

• Patients included in the study CT 01614704
• Informed and written consent
• Affiliated to the National Social Security System

Exclusion Criteria:

• Impossibility to submit at the study procedures due to geographic, social or mental reasons
• Patient deprived of their liberty or under guardianship or tutorship.