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| ID | Type | Description | Link |
|---|---|---|---|
| R01HL143792 | U.S. NIH Grant/Contract | View source | |
| R21MD013650 | U.S. NIH Grant/Contract | View source |
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| Name | Class |
|---|---|
| National Heart, Lung, and Blood Institute (NHLBI) | NIH |
| National Institute on Minority Health and Health Disparities (NIMHD) | NIH |
| University of Massachusetts, Lowell | OTHER |
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The overall goal is to identify trends and longitudinal associations in psychosocial, food-related, and cardiometabolic risk factors that can guide public health priorities and future research needs aimed at reducing cardiovascular-related disparities in Puerto Rico. To this end, investigators will establish 'PROSPECT: Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic disease Trends', an island-wide, longitudinal population cohort of 2,500 adults (30-75 years) in PR recruited with a community-wide sampling strategy, and assessed in a network of several partner clinics across the island. The study will collect comprehensive data on multiple psychosocial, dietary, and food-related factors, CVD biological markers, and medical record data, with follow-up at 2-years, and will assess variations by urban-rural area and by timing before-after Maria.
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| Measure | Description | Time Frame |
|---|---|---|
| Number of participants with self-reported medically-diagnosed chronic diseases | Estimate the prevalence and incidence of chronic diseases (and their dietary and psychosocial risk factors) | 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| Difference in the number of participants with self-reported medically-diagnosed chronic diseases living urban vs. rural area | Estimate differences in prevalence and changes in chronic diseases (and their dietary and psychosocial risk factors) in urban vs. rural area | 4 years |
| Measure | Description | Time Frame |
|---|---|---|
| Risk of clinically-measured metabolic syndrome (e.g. high blood pressure, elevated adiposity, elevated blood glucose, and out-of-normal-range blood lipids), according to dietary and psychosocial risk factors | Determine risk of biological metabolic risk factors by changes in psychosocial factors or diet-related factors | 4 years |
Inclusion Criteria:
Exclusion Criteria:
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Convenience community-wide sample of eligible adults living in all of Puerto Rico.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Josiemer Mattei, PhD | Contact | 6174323017 | jmattei@hsph.harvard.edu | |
| Martha Tamez, ScD | Contact | 6174323017 | m.tamez@mail.harvard.edu |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Puerto Rico Consortium for Clinical Investigation | Recruiting | San Juan | 00927 | Puerto Rico |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 33083832 | Background | Mattei J, Tucker KL, Falcon LM, Rios-Bedoya CF, Kaplan RM, O'Neill HJ, Tamez M, Mendoza S, Diaz-Alvarez CB, Orozco JE, Acosta Perez E, Rodriguez-Orengo JF. Design and Implementation of the Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic Disease Trends (PROSPECT). Am J Epidemiol. 2021 May 4;190(5):707-717. doi: 10.1093/aje/kwaa231. | |
| 35019984 | Result | Mattei J, Tamez M, O'Neill J, Haneuse S, Mendoza S, Orozco J, Lopez-Cepero A, Rios-Bedoya CF, Falcon LM, Tucker KL, Rodriguez-Orengo JF. Chronic Diseases and Associated Risk Factors Among Adults in Puerto Rico After Hurricane Maria. JAMA Netw Open. 2022 Jan 4;5(1):e2139986. doi: 10.1001/jamanetworkopen.2021.39986. |
| Label | URL |
|---|---|
| Study website | View source |
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IPD will be managed and distributed observing NIH and IRB policies on the dissemination and sharing of research results. Study information and requests for data will be available immediately upon the data being de-identified and properly revised for quality control on the study website.
2-years
The requested data will be shared with investigators via a secured, password-protected software website.
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| San Diego State University |
| OTHER |
| Albert Einstein College of Medicine | OTHER |
| Puerto Rico Consortium for Clinical Investigations | UNKNOWN |
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Blood, urine, saliva, hair.
| 36048184 | Result | Lopez-Cepero A, O'Neill HJ, Marrero A, Falcon LM, Tamez M, Rodriguez-Orengo JF, Mattei J. Association between adverse experiences during Hurricane Maria and mental and emotional distress among adults in Puerto Rico. Soc Psychiatry Psychiatr Epidemiol. 2022 Dec;57(12):2423-2432. doi: 10.1007/s00127-022-02355-2. Epub 2022 Sep 1. |
| 37395692 | Result | Xu W, Lopez-Cepero A, O'Neill HJ, Plym A, Austin SB, Mattei J. Food Insecurity Is Associated With Dysfunctional Eating Behaviors Among Adults in Puerto Rico. J Nutr Educ Behav. 2023 Sep;55(9):644-650. doi: 10.1016/j.jneb.2023.05.255. Epub 2023 Jul 1. |
| Facebook page | View source |
| ID | Term |
|---|---|
| D006331 | Heart Diseases |
| D006973 | Hypertension |
| D009765 | Obesity |
| D050171 | Dyslipidemias |
| D024821 | Metabolic Syndrome |
| D002318 | Cardiovascular Diseases |
| D002908 | Chronic Disease |
| D007249 | Inflammation |
| D013315 | Stress, Psychological |
| D003863 | Depression |
| D005247 | Feeding Behavior |
| ID | Term |
|---|---|
| D014652 | Vascular Diseases |
| D050177 | Overweight |
| D044343 | Overnutrition |
| D009748 | Nutrition Disorders |
| D009750 | Nutritional and Metabolic Diseases |
| D001835 | Body Weight |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D052439 | Lipid Metabolism Disorders |
| D008659 | Metabolic Diseases |
| D007333 | Insulin Resistance |
| D006946 | Hyperinsulinism |
| D044882 | Glucose Metabolism Disorders |
| D020969 | Disease Attributes |
| D010335 | Pathologic Processes |
| D001526 | Behavioral Symptoms |
| D001519 | Behavior |
| D001522 | Behavior, Animal |
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