Assessment of Feasibility and Acceptability of Personalized Breast Cancer Screening

Personalized Breast Cancer Screening: Assessment of Its Feasibility and Acceptability in the National Health System

The overall objective is to assess the acceptability and feasibility of offering personalized breast cancer (BC) screening.

The specific objectives are: 1) To design an information system; 2) To evaluate the barriers and facilitators of the coordination of health care services and the screening program; 3) To develop a proof of concept of personalized screening; and 4) To evaluate cost-effectiveness.

Methodology:

1. Prototype information system with basal and longitudinal variables relevant to a personalized screening system;
2. Qualitative study with focus groups and survey. The attitude and acceptability on a sample of 210 health professionals will be assessed;
3. Prospective observational study, for proof of concept. Participants will be professionals working in Primary Care, Population Breast Screening Program, or Hospital Breast Unit. It will include 385 women, aged 40-50 from the city of Lleida. Various indicators of acceptability and feasibility will be assessed in women and health professionals;
4. Probabilistic analytical models will be used to evaluate cost-effectiveness.

The present protocol addresses the specific objective number 3, the proof of concept of personalised screening.

Expected results: The investigators expect to provide valuable and necessary information for the design of personalized screening.

Inclusion Criteria:

• Not having had a mammogram in the last 12 months or with a mammogram in this period available to evaluate breast density.
• Sign the informed consent.

Exclusion Criteria:

• Previous diagnosis of breast cancer.
• Breast study in process.
• Fulfill clinical criteria defined by the Medical Oncology Spanish Society (SEOM to refer to the genetic counseling unit in cancer.
• Do not understand or speak Catalan or Spanish.
• Cognitive disability for mental or mental illness.
• Physical disability that prevents a mammogram.