Factors Associated With Residual Disease In The Central Cone

Factors Associated With Residual Disease In The Central Cone: A Disease Prediction Model

Cervical conization using the loop electrosurgical excision procedure (LEEP) is the standard treatment for patients with high-grade cervical intraepithelial neoplasia. Several studies have shown that excising a central cone reduces the rate of positive endocervical margins. The purpose of this study is to identify clinicopathological factors associated with residual disease in the central cone and to develop a predictive model to better determine which patients may require this additional procedure.

This study pretends to create a retrospective database including all patient who underwent a loop electrosurgical excision procedure by treatment for high-grade cervical intraepithelial neoplasia and create a a predictive model for top-hat resection in patients with high grade CIN

Inclusion Criteria:

• patients who underwent a loop electrosurgical excision procedure (LEEP)

Exclusion Criteria:

• a diagnosis of micro-invasion or nonsquamous histology
• less than six months of follow-up
• incomplete information in their clinical charts.