To date, no transplant has allowed pregnancy from a donor in a state of brain death. One of the main reservations lies in the ischemic properties of the uterine graft between the sampling time and the grafting time.

Investigators propose to carry out a prospective monocentric study at the University Hospitals of Strasbourg in 2018/2019: the objective would be to study physiologically the time of ischemia of the uterine muscle The objective is to carry out a preparatory study on healthy uteri to study the ischemic properties of uterine muscle from living markers: study of mitochondrial respiration and free radical production on uterine muscle samples If the markers are reliable, they would then be used to measure the ischemia of whole uteri collected at the end of the multi-organ retrieval process from donors in a state of brain death and stored in tissue survival media.

Inclusion criteria:

• - Adult patient
• Patient benefiting from the routine management of a programmed hysterectomy by vaginal, laparoscopic or laparotomy for benign pathologies (fibroma, adenomyosis, genital prolapse,...) within the CMCO
• Patient consenting to the use of cells from her uterus for incineration for research purposes
• Patient giving her consent for the use of her medical data for the purposes of this research.
• Patient agreeing to participate in the study

Exclusion criteria:

• - Patient refusing to participate in the study
• Patient under the protection of justice
• Patient under guardianship or curatorship
• Suspicion of gynaecological malignant pathology
• Pregnant or breastfeeding woman
• Impossibility to give the subject informed information (difficulties in understanding the subject...)

Patient benefiting from the routine management of a programmed hysterectomy by vaginal, laparoscopic or laparotomy for benign pathologies