The SNAP Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Neuropathic Post-Amputation Pain

The SNAP Trial: SPRINT® Peripheral Nerve Stimulation for the Treatment of Neuropathic Post-Amputation Pain in a Randomized, Double-blinded, Placebo-controlled, Multicenter Trial

The purpose of this study is to determine if pain can be relieved by delivering small amounts of electricity (called "electrical stimulation") to the nerves in an individual's amputated leg.This study will involve the use of a Peripheral Nerve Stimulation (PNS) System that is made by SPR Therapeutics (the sponsor of the study). The PNS System was cleared by the FDA for up to 60 days of use for the management of chronic pain, including extremity (leg) pain.

Key Inclusion Criteria:

• At least 21 years old
• Lower extremity amputation
• Experiencing residual limb (stump) and/or phantom limb pain
• Healed amputation and healthy residual limb based upon the investigator's evaluation

Key Exclusion Criteria:

• Conditions with increased risk of infection (e.g., compromised immune system or history of recurrent skin infections)
• Implanted electronic device
• Pregnancy