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| Name | Class |
|---|---|
| Eurofins | INDUSTRY |
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The purpose of the study is to evaluate the sensitivity and specificity of the Target Enriched Multiplex (TEM) polymerase chain reaction (PCR) platform for the rapid molecular diagnosis and treatment of odontogenic deep space neck infections.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Subjects with advanced deep space odontogenic infection | Experimental | Subjects will be diagnosed via two methods: 1. Target Enriched Multiplex PCR (TEM- PCR) and 2. Standard microbial culture. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Target Enriched Multiplex PCR (TEM- PCR) | Diagnostic Test | Target Enriched Multiplex PCR (TEM- PCR) assays will be performed and will probe for the typical array of advanced deep space odontogenic infections, as well as MRSA resistance, clindamycin resistance, and the presence of Panton-Valentine leukocidin (PVL) toxin, a toxin produced by some bacteria. |
| Measure | Description | Time Frame |
|---|---|---|
| Specificity as assessed by number of participants who had matching results between TEM-PCR and standard microbial culture | Baseline (at the time the sample was obtained from the patient) |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Jonathon Jundt, DDS, MD | The University of Texas Health Science Center, Houston | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Th University of Texas Health Science Center at Houston | Houston | Texas | 77030 | United States |
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| Microbial culture | Diagnostic Test | Standard diagnosis by microbial culture. |
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