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The purpose of this study is to determine the ability to use pharmacogenetic testing in a joint replacement practice to prescribe the most effective pain medicine for a specific patient.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Control Group | No Intervention | Subjects in this arm will receive the standard postoperative pain prescription protocol. | |
| Pharmacogenomics Guided Group | Active Comparator | Subjects in this group will receive postoperative pain prescriptions based on the results of pharmacogenomic testing. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Pharmacogenomics Testing | Diagnostic Test | The doctor will use genetic test results to prescribe medications that are a most effective for subject. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Genetic variants | Percent of subject with genetic variants affecting pain medication | 10 days postoperative |
| Measure | Description | Time Frame |
|---|---|---|
| pain levels | 0-10 subjective pain scale | 10 days postoperatively |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| William Hamilton, MD | Anderson Orthopaedic Research Institute | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Anderson Orthopaedic Research Institute | Alexandria | Virginia | 22307 | United States |
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