Virtual Prism Adaptation Therapy on Hemispatial Neglect

Effects of Virtual Prism Adaptation Therapy in Stroke Patients With Hemispatial Neglect

The purpose of this study is to investigate the effect of virtual prism adaptation therapy on hemispatial neglect in chronic stroke patients. This study is the randomized, double-blind, sham-controlled, cross-over design. Total 10 patients will be allocated randomly to either real virtual prism adaptation therapy or sham therapy with the wash-out period of more than 2 weeks. Two sessions (20min/session) per day, for 5days (total 10 sessions) will be provided. Behavioral outcomes will be measured before and after completing a total of 10 sessions therapy.

Inclusion Criteria:

• 3 months after stroke onset
• 2 or more tests indicative of hemispatial neglect in following 3 tests: 1)line bisection test, 2)Albert's test, 3)Drawing test.
• Ability to recognize the target object, hand trajectory in the immersive virtual reality
• 16 points or more in the Korean version of mini-mental state examination

Exclusion Criteria:

• Previous stroke or traumatic brain injury history
• Can not cooperate during the therapy, due to delirium or aphasia
• Unstable medical conditions
• Severe psychiatric symptoms that interfere with the therapy participation (e.g. severe depression, agitation, psychotic symptoms)
• Pregnancy
• Can not maintain sitting posture