Exploratory Study on Two Different Doses of VML-0001 on the Effects on Vaginal pH in Healthy Post-Menopausal Women

A Phase II, Open-label, Single-Centre, Randomized, Cross-over, Exploratory Study on Two Different Doses of VML-0001, the Base Formulation of Viramal's pH Regulating and Vaginal Moisturizing Cream, on the Effects on Vaginal pH in Healthy Post-Menopausal Women

The study is designed to determine the effect on vaginal pH and the duration of action measured on the ability of the base formulation to reduce the vaginal pH

Inclusion Criteria:

• be greater than 45 years
• no positive findings on screening gynaecological examination
• negative smear test within the last 5 years

Exclusion Criteria:

• has signs of vaginal infection
• has evidence of alcohol abuse
• has used hormonal replacement therapy in three months prior to study entry