Genetic Analysis of Pediatric Psoriasis

Genetic Analysis of Pediatric Psoriasis

This study will ascertain approximately 150 subjects, which will include pediatric psoriasis patients diagnosed before age 12, parents not affected by psoriasis, and if a family history is indicated, up to third-degree family members. Saliva (or buccal swabs in the case of infants) will be obtained for DNA isolation.

Inclusion Criteria:

• Patients (of any age) who developed psoriasis before 12 years of age and who have no family history of psoriasis in either parent.
• Parents of patients who developed psoriasis before 12 years of age
• Up to third-degree family members (first cousin, grandparent, great-grandparent) with or without psoriasis, if family history is indicated.

Exclusion Criteria:

• Patients, parents, and other family member unable to give a saliva or buccal swab sample.
• Patients, parents, and other family member unable to give written informed consent.