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The purpose of this study is to compare the efficacy and cost-effectiveness of a Computer-based Training for Cognitive Behavioural Therapy (CBT4CBT) to treatment as usual in outpatients seeking treatment for substance use disorder.
Fifty-two adult outpatients seeking treatment for substance use disorder from the Centre for Addiction and Mental Health Addictions Program will be randomized to receive either a computer-based training for cognitive behavioural therapy or treatment as usual for eight weeks. Participants will complete interviews, questionnaires, and other assessments (urine toxicology and physiological assessments) at week 0, at week 8, and at 6 month follow-up). Measures will assess alcohol and drug consumption, substance use disorder symptoms and associated features, quality of life, and healthcare costs.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Online Cognitive Behavioural Therapy | Experimental | Computer-based training for cognitive behavioural therapy (CBT4CBT) consists of seven modules, and includes a series of interactive videos presenting characters portrayed by professional actors struggling with real-life situations. These characters first experience a common risky situation or problem and then demonstrate the application of a targeted skill. The program further comprises games and interactive exercises to teach and model effective use of skills and strategies. |
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| Treatment as Usual | Active Comparator | Treatment as usual consists of weekly group and/or individual psychotherapy as determined by the clinical team. Psychotherapy will include structured relapse prevention, include cognitive and behavioural techniques, motivational enhancement, mindfulness, and specialized topics (e.g., vocational training, rainbow services) as appropriate. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Computer-based Training for Cognitive Behavioural Therapy | Behavioral | Interactive content organized into seven modules, illustrating real-life scenarios associated with common risky situations, which illustrate the application of targeted skills and strategies |
| Measure | Description | Time Frame |
|---|---|---|
| Timeline Follow-Back (TLFB) | Frequency (days) of substance use over the past 30 days | 30 days |
| Measure | Description | Time Frame |
|---|---|---|
| Urine Toxicology Screen | Determine substance use in past 30 days | 30 days |
| Addiction Severity Index (ASI) | Substance Use Disorder symptom severity Subscale scores are calculated for 7 domains (medical, employment/support status, alcohol, drug, legal, family/social and psychological). Subscale scores are summed scores ranging from 0-1 with higher scores indicating greater problem severity. |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Lena C. Quilty, PhD | Campbell Family Mental Health Research Institute, CAMH | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Campbell Family Mental Health Research Institute, CAMH | Toronto | Ontario | M5S 2S1 | Canada |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 38783836 | Derived | Patel A, Corman M, de Oliveira C, Mason J, Some N, Downie D, Jain E, Patterson M, Cunningham JA, George TP, Le Foll B, Quilty LC. Computer-Based Training for Cognitive Behavioural Therapy for Substance Use Disorder: A Randomized Controlled Trial Including Quantitative and Qualitative Health and Economic Outcomes: Formation informatisee pour la therapie cognitivo-comportementale pour les troubles lies a l'usage de substances : un essai randomise controle y compris les resultats quantitatifs et qualitatifs en matiere de sante et d'economie. Can J Psychiatry. 2025 Jan;70(1):9-20. doi: 10.1177/07067437241255100. Epub 2024 May 24. |
| Label | URL |
|---|---|
| Information about research at the Centre for Addiction and Mental Health | View source |
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| Treatment As Usual | Behavioral | Treatment as usual will include standard psychosocial care determined to be appropriate or necessary, on an individual patient basis. |
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| 30 days |
| WHO Quality of Life (WHOQOL-BREF) | Quality of Life Subscale scores are calculated for 4 domains (physical health, psychological, social relationships and environment) and for "overall" and "general health" quality of life. Subscale scores have a range of 0 to 100 with higher scores indicating greater quality of life. | 4 weeks |
| Program and Client Costs-Substance Abuse Treatment (PACC-SAT) | Healthcare Costs | 7 days |
| ID | Term |
|---|---|
| D019966 | Substance-Related Disorders |
| ID | Term |
|---|---|
| D064419 | Chemically-Induced Disorders |
| D001523 | Mental Disorders |
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| ID | Term |
|---|---|
| D015928 | Cognitive Behavioral Therapy |
| D013812 | Therapeutics |
| ID | Term |
|---|---|
| D001521 | Behavior Therapy |
| D011613 | Psychotherapy |
| D004191 | Behavioral Disciplines and Activities |
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