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| Name | Class |
|---|---|
| Ankara University | OTHER |
| University Hospital Tuebingen | OTHER |
| Imperial College Healthcare NHS Trust | OTHER |
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The LiverVision® software was designed to provide three-dimensional (3D) visualisation of the liver using Computed Tomography (CT) scans. It provides semi-automated volumetry measurements, vascular structure and territory tools.
Liver volumetry has been widely used in liver surgery and living donor liver transplantation to estimate the future liver remnant or the required liver volume for the recipient, respectively.
Liver volumetry is typically performed using CT imaging with specially designed software. Such manual measurements are time consuming and there is an ongoing debate whether the they reflect the actual liver volume when performed by radiologists or surgeons as well as according to the different software currently available in the market.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Living liver donors | This is a group of living liver donors that underwent a CT prior to donating their partial liver to a recipient. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Liver volumetry of the graft on CT | Diagnostic Test | Preoperative liver volumetry using the CT images of the potential living liver donors. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Accuracy of the LiverVision® software volumetric measurements | Accuracy of the LiverVision® software volumetric measurements assessed by correlation and agreement statistics with the manual volumetric measurements as well as the actual graph weight (reference standard). | Baseline (CT performed prior to donation). |
| Measure | Description | Time Frame |
|---|---|---|
| Learning curve of the raters | Assessment of the learning curve of the raters when using LiverVision® software assessed by the time required for the volumetric measurements and the accuracy of the results. | Baseline (CT performed prior to donation). |
| Certainty and accuracy of the volumetric measurements. |
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Inclusion Criteria:
Exclusion Criteria:
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Consecutive living liver donors that underwent a CT prior to liver donation. The raters will be 6 surgeons and 6 radiologists, both junior and senior.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Dimitri A Raptis, MD, MSc, PhD | Contact | +447584560889 | dimitri.raptis@nhs.net | |
| Massimo Malago', MD, PhD | Contact | +442077940500 | massimo.malago@nhs.net |
| Name | Affiliation | Role |
|---|---|---|
| Massimo Malago', MD, PhD | Royal Free Hospital NHS Foundation Trust | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Universitätsklinikum Tübingen | Recruiting | Tübingen | 72076 | Germany |
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| Label | URL |
|---|---|
| Data management platform for the LiverVision.org Study | View source |
| Cloud Graphical User Interface for R Statistics, the statistical analysis software | View source |
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There is no plan for sharing individual participant data.
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| ID | Term |
|---|---|
| D008107 | Liver Diseases |
| D008113 | Liver Neoplasms |
| ID | Term |
|---|---|
| D004066 | Digestive System Diseases |
| D004067 | Digestive System Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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Correlation of the degree of certainty of the raters with the accuracy of their volumetric measurements. |
| Baseline (CT performed prior to donation). |
| Comparison | Comparison of the accuracy among junior, senior, surgeons and radiologists (4 groups) | Baseline (CT performed prior to donation). |
| Ankara Üniversitesi Tıp Fakültesi Cebeci Araştırma ve Uygulama Hastanesi | Recruiting | Ankara | 06620 | Turkey (Türkiye) |
|
| Royal Free Hospital | Recruiting | London | NW3 2QG | United Kingdom |
|