Janus Kinase 1 in Vitiligo & Psoriasis

Expression of Janus Kinase 1 in Vitiligo and Psoriasis Before and After Narrow Band UVB: a Case-Control Study

Assessment of the level of JAK1 in both vitiligo and psoriasis patients before and after treatment with NB-UVB which is considered a gold standard therapy for both diseases.

Inclusion Criteria:

• age above 12 years of age.
• psoriasis vulgaris or non-segmental vitiligo
• patients who received no systemic or topical treatment at least 6 weeks prior to enrollment into the study.

Exclusion Criteria:

• psoriasis patients with erythrodermic psoriasis, pustular psoriasis or associated psoriatic arthritis
• vitiligo patients with segmental or universal vitiligo were excluded from the study.
• any patient with a photosensitive disorder or any contraindication to phototherapy exposure, e.g., history or presence of malignant or premalignant skin lesions.