The Change of Gut Microbiota After Bowel Preparation and the Effect of Probiotics

The Change of Gut Microbiota After Bowel Preparation and the Effect of Probiotics: Randomized Controlled, Open-label Trial

The purpose of this study is to investigate the relationship between the change of intestinal bacterial flora and the recovery, and the incidence of symptoms such as abdominal discomfort after colonoscopy. And the investigators will also analyze the effects of probiotics on the degree of change, recovery, and symptom development in intestinal flora.

The investigators divided two groups. (total number = 100 subjects)

1. with probiotics group - 50 subjects

   • Participants included in this group will be taken probiotics for 1 month after bowel preparation for colonoscopy.

2. without probiotics group - 50 subjects

   • Participants included in this group will not be taken probiotics for 1 month after bowel preparation for colonoscopy.

Inclusion Criteria:

• adults between the age of 30 and 70

Exclusion Criteria:

• subjects with cancer or IBD (inflammatory bowel disease)
• subjects with history of abdominal surgery
• subjects who take medication related to gastrointestinal motility within 3 months
• subjects who take antibiotics within 3 months