Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
Parkinson's disease is a progressive, degenerative neurological disease associated with profound changes in the quality of life of its survivors. Recent evidence has demonstrated the potential use of transcranial direct current stimulation (tDCS) to modulate cerebral excitability and movement control in neurological chronic conditions. However, few studies have investigated the effects of tDCS on postural control in patients with Parkinson's disease. This study aims to investigate the effect of bihemispheric tDCS on postural control in people with Parkinson's disease. Participants will be randomized to receive a single session of anodal and sham bihemispheric tDCS (7 days between each type of stimulation).
Primary clinical outcome (balance) will be collected before and immediately after tDCS. The data will be collected by a blind examiner to the treatment allocation.
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Anodal tDCS | Experimental | Bihemispheric tDCS applied over primary motor cortex. Dose: 2mA, 20 minutes |
|
| Sham tDCS | Sham Comparator | Bihemispheric tDCS applied over primary motor cortex. Dose: 2mA, 20 minutes (30s ON) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Transcranial direct current stimulation | Procedure | Transcranial direct current stimulation is a noninvasive technique of neuronal modulation that has been used in different chronic neurological conditions, including Parkinson's disease. |
| Measure | Description | Time Frame |
|---|---|---|
| Change from COP - AP axis | Postural instability will be evaluated using a force plate to record center of pressure displacement (COP) in antero-posterior (AP) axis in centimeters. | Baseline and Post-tDCS (immediately after tDCS) |
| Change from COP - ML axis | Postural instability will be evaluated using a force plate to record center of pressure displacement (COP) in Mediolateral (ML) axis in centimeters. | Baseline and Post-tDCS (immediately after tDCS) |
| Change from COP - area | Postural instability will be evaluated using a force plate to record center of pressure displacement (COP) area (cm²). | Baseline and Post-tDCS (immediately after tDCS) |
Not provided
| Measure | Description | Time Frame |
|---|---|---|
| Adverse effects | Adverse effects will be evaluated using structured questionnaire | Immediately after tDCS |
Inclusion Criteria:
Medical diagnosis of idiopathic Parkinson's disease present for at least 12 months
In clinical follow-up and pharmacological treatment by a responsible physician
Parkinson's classification of 1.5-3 according to the Hoehn and Yahr scale
Signing of the free and informed consent form-
Exclusion Criteria:
Use any associated orthopedic device to aid gait or balance control
Signs of severe dementia (evaluated by the Mini-Mental State Examination - MMSE)
Diagnosis of other neurological disorders (including those of central and peripheral nature)
Previous treatment with tDCS
Medical diagnosis of psychiatric illnesses with the use of centrally acting medications (depressants)
The use of pacemakers or other implanted devices.-
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Physical Therapy. Federal University of Piaui | ParnaÃba | Piauà | 64202020 | Brazil |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| ID | Term |
|---|---|
| D010300 | Parkinson Disease |
| ID | Term |
|---|---|
| D020734 | Parkinsonian Disorders |
| D001480 | Basal Ganglia Diseases |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
Not provided
Not provided
| ID | Term |
|---|---|
| D065908 | Transcranial Direct Current Stimulation |
| ID | Term |
|---|---|
| D004599 | Electric Stimulation Therapy |
| D013812 | Therapeutics |
| D003295 | Convulsive Therapy |
| D013000 | Psychiatric Somatic Therapies |
Not provided
Not provided
Not provided
Not provided
Not provided
Not provided
| D009422 | Nervous System Diseases |
| D009069 | Movement Disorders |
| D000080874 | Synucleinopathies |
| D019636 | Neurodegenerative Diseases |
| D004191 | Behavioral Disciplines and Activities |
| D004597 | Electroshock |
| D011580 | Psychological Techniques |