Men who have Sex with Men (MSM) attending an addiction care center for past or present mild, moderate or severe substance-related disorder(s) according to DSM-V criteria, occurring in a sexual context and concerning cathinones, GHB/GBL, methamphetamine, cocaine and/or ketamine.

Men who have Sex with Men (MSM) consulting for a PrEP (HIV Pre-Exposure Prophylaxis) prescription who have never used cathinones, GHB/GBL, methamphetamine, cocaine or ketamine before or during sex.

• Questionnaires : PDQ-4+ (personality disorders), HAD (Anxiety and Depression), AUDIT-c (Alcohol consumption), CTQ-SF (Childhood Trauma Questionnaire).
• Semi-structured interview : Evaluation of socio-demographic characteristics, psychiatric and addiction comorbidities, sexually transmitted infections, sexual practices, sexual dysfunction, hypersexual disorder.

Positive score for 1 or more DSM-V personality disorders(PD) using French version of the PDQ4+,Personality Diagnostic Questionnaire-Version4,comprising:

• Combined score of overall personality disturbance (ranges0 to 93);higher values reflect a more important personality disturbance
• Borderline PD:Score Ranges(SR) 0 to 9,positive(+) if ≥ 5
• Narcissistic PD:SR 0 to 9,+ if ≥5
• Histrionic PD:SR 0 to 8,+ if ≥5
• Antisocial PD:SR 0 to 8,+ if ≥4 and criteria 99 positive
• Avoidant PD:SR 0 to 7,+ if ≥4
• Dependent PD:SR 0 to 8,+ if ≥5
• Obsessive-Compulsive PD:SR 0 to 8,+ if ≥4
• Paranoid PD:SR 0 to 7,+ if ≥4
• Schizoid PD:SR 0 to 7,+ if ≥4
• Schizotypal PD:SR 0 to 9,+ if ≥5
• Questionnaire must be interpreted with caution if 1 of the 2 "Suspect Questionnaire" items is +, or if at least 2 of the 4 "Too Good" items are +
• Negativistic and depressive PD are evaluated with the PDQ4+ but are not part of the outcome measures in the study