NSAID vs Steroid in Trabeculectomy Wound Management

An Investigator-Initiated Multicenter Prospective Clinical Trial to Examine the Efficacy of Peri-operative NSAID vs Steroid Treatment in Trabeculectomy Wound Management

This study will examine the efficacy of steroid vs NSAID treatment in relation to trabeculectomy wound management. Eligible study participants will be randomized to receive either steroid or NSAID topical treatment one week post-trabeculectomy. Each group will dose with their assigned study treatment until three months post-trabeculectomy. Study participants will be followed for twelve months post-trabeculectomy.

Inclusion Criteria:

• Adult patients over the age of 18 years
• Uncontrolled open angle glaucoma
• Scheduled to undergo stand-alone trabeculectomy
• No previous incisional glaucoma surgery
• No ocular surgery of any kind in prior 6 months

Exclusion Criteria:

• steroids and/or NSAIDs contraindicated
• poor corneal epithelial health