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The aim of the study is to assess whether the value of neutrophil-lymphocyte count ratio from the routine preoperative blood test may predict lung tumors' grading.
Lung cancer remains as one of the leading causes of death among oncology patients. Close connection between inflammation and pathogenesis of some neoplasms was determined in a number of studies. Some studies show promise that ratio of neutrophil to lymphocyte count (NLCR) may be recognized as a prognostic marker for several carcinomas: renal, lung and colorectal. The aim of the study is to assess whether the value of neutrophil-lymphocyte count ratio from the routine preoperative blood test may predict lung tumors' grading. During routine preoperative blood tests complete blood count is done and NLCR, WBC, neutrophil and lymphocyte count is noted. After the thoracic surgery intervention and histopathological examination grading of lung tumor is noted.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Observational Group | Group of patients with lung tumor qualified for thoracic surgery intervention with routine, preoperative complete blood count test and routine postoperative histopathological examination of lung tumor. |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Complete blood count | Diagnostic Test | During routine preoperative blood test complete blood count is taken. |
|
| Measure | Description | Time Frame |
|---|---|---|
| Neutrophil-lymphocyte count ratio | Neutrophil-lymphocyte count ratio is measured during routine preoperative blood tests. | From October 1, 2014 to October 15, 2018 |
| Measure | Description | Time Frame |
|---|---|---|
| Neutrophil count | Neutrophil count is measured during routine preoperative blood tests. | From October 1, 2014 to October 15, 2018 |
| Lymphocyte count | Lymphocyte count is measured during routine preoperative blood tests. |
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Inclusion Criteria:
Exclusion Criteria:
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Consecutive thoracic surgery patients admitted to SPSK nr 1 in Zabrze between October 2014 and October 2018 with lung tumor qualified for thoracic surgery intervention
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| Name | Affiliation | Role |
|---|---|---|
| Hanna MisioĊek, MD PhD | Medical University of Silesia | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Samodzielny Publiczny Szpital Kliniczny nr 1 | Zabrze | Silesian Voivodeship | 41-800 | Poland |
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| ID | Term |
|---|---|
| D008175 | Lung Neoplasms |
| ID | Term |
|---|---|
| D012142 | Respiratory Tract Neoplasms |
| D013899 | Thoracic Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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| ID | Term |
|---|---|
| D001772 | Blood Cell Count |
| ID | Term |
|---|---|
| D002452 | Cell Count |
| D003584 | Cytological Techniques |
| D019411 | Clinical Laboratory Techniques |
| D019937 | Diagnostic Techniques and Procedures |
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| Histopathological examination | Other | Routine postoperative histopathological examination of lung tumor. |
|
| From October 1, 2014 to October 15, 2018 |
| Leucocyte count | Leucocyte count is measured during routine preoperative blood tests. | From October 1, 2014 to October 15, 2018 |
| D008171 |
| Lung Diseases |
| D012140 | Respiratory Tract Diseases |
| D003933 | Diagnosis |
| D006403 | Hematologic Tests |
| D008919 | Investigative Techniques |
| D002468 | Cell Physiological Phenomena |
| D001790 | Blood Physiological Phenomena |
| D002943 | Circulatory and Respiratory Physiological Phenomena |