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| Name | Class |
|---|---|
| Fondation de France | OTHER |
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The purpose of this study is to assess the incidence and risk factors of prolonged grief in family members of patients died in French palliative care units and to explore experience of bereaved families to build a scientifically valid management prevention program.
There is hardly knowledge on how bereavement is treated in palliative care patient's relatives. The field of bereavement needs studies that validate the theoretical underpinning of the research area. This study will depict the grieving process of individuals having lost a relative in palliative care in France. Having baseline data of incidence of prolonged grief, risk factors of relative's prolonged grief and identification of risk factors associated with the management of end-of-life issues in palliative care will contribute to target interventions that should help decrease bereaved families burden.
The investigator designed a quantitative study to assess the psychological effect of families after the death of the patient in palliative care unit and a qualitative study to examine the grieving prolonged process.
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence of prolonged grief in bereaved family members | Inventory Grief Disorder > 25 | 6 months after patient's death in palliative care unit |
| Risk factors of prolonged grief in bereaved family members | Hierarchical logistic regression models with a random effect center after selection of variables by univariate analysis then introduced in a multivariate analysis | 6 months after patient's death in palliative care unit |
| Measure | Description | Time Frame |
|---|---|---|
| Post traumatic stress disorder in bereaved family members | Impact of event Scale-revised > 22 | 6 months after patient's death in palliative care unit |
| Anxiety and depression symptoms in bereaved family members |
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Inclusion Criteria:
Exclusion Criteria:
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The participating palliative care units belong to the French Society of Palliative Care (SFAP) and are selected using the list of the different French units on their website. An invitation of participation is sent to the clinical responsible of each unit.
The participating units belong to university, community and private hospitals.
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| Name | Affiliation | Role |
|---|---|---|
| Jean-François Timsit, MD, PhD | INSERM 1137, IAME, Paris Diderot University, Paris | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| French British Institute | Levallois-Perret | 92300 | France |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 25707938 | Result | Fasse L, Flahault C, Bredart A, Dolbeault S, Sultan S. Describing and understanding depression in spouses of cancer patients in palliative phase. Psychooncology. 2015 Sep;24(9):1131-7. doi: 10.1002/pon.3777. Epub 2015 Feb 24. | |
| 25614168 | Result | Kentish-Barnes N, Chaize M, Seegers V, Legriel S, Cariou A, Jaber S, Lefrant JY, Floccard B, Renault A, Vinatier I, Mathonnet A, Reuter D, Guisset O, Cohen-Solal Z, Cracco C, Seguin A, Durand-Gasselin J, Eon B, Thirion M, Rigaud JP, Philippon-Jouve B, Argaud L, Chouquer R, Adda M, Dedrie C, Georges H, Lebas E, Rolin N, Bollaert PE, Lecuyer L, Viquesnel G, Leone M, Chalumeau-Lemoine L, Garrouste M, Schlemmer B, Chevret S, Falissard B, Azoulay E. Complicated grief after death of a relative in the intensive care unit. Eur Respir J. 2015 May;45(5):1341-52. doi: 10.1183/09031936.00160014. Epub 2015 Jan 22. |
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Hospital anxiety and depression scale ≥ 8
| 6 months after patient's death in palliative care unit |
| Anxiety and depression symptoms in family members | Hospital anxiety and depression scale ≥ 8 | Between between day 3 and day 5 after patient admission in the palliative care unit |
| Report of the families' grief experience in those who have signs of prolonged grief according to the Inventory of Complicated Grief questionnaire with a score > 25 | Interpretative Phenomenological Analysis | Between 6 and 12 months after the patient' death. |
| 29173097 | Result | Flahault C, Dolbeault S, Sankey C, Fasse L. Understanding grief in children who have lost a parent with cancer: How do they give meaning to this experience? Results of an interpretative phenomenological analysis. Death Stud. 2018 Sep;42(8):483-490. doi: 10.1080/07481187.2017.1383951. Epub 2018 Jan 24. |
| 24115499 | Result | Fasse L, Sultan S, Flahault C, Mackinnon CJ, Dolbeault S, Bredart A. How do researchers conceive of spousal grief after cancer? A systematic review of models used by researchers to study spousal grief in the cancer context. Psychooncology. 2014 Feb;23(2):131-42. doi: 10.1002/pon.3412. Epub 2013 Sep 30. |
| 36878669 | Derived | Garrouste-Orgeas M, Marche V, Pujol N, Michel D, Evin A, Fossez-Diaz V, Perruchio S, Vanbesien A, Verlaine C, Copel L, Kaczmarek W, Birkui de Francqueville L, Michonneau-Gandon V, de Lariviere E, Poupardin C, Touzet L, Guastella V, Mathias C, Mhalla A, Bouquet G, Richard B, Gracia D, Bienfait F, Verliac V, Ranchou G, Kirsch S, Flahault C, Loiodice A, Bailly S, Ruckly S, Timsit JF. Incidence and risk factors of prolonged grief in relatives of patients with terminal cancer in French palliative care units: The Fami-Life multicenter cohort study. Palliat Support Care. 2024 Oct;22(5):961-970. doi: 10.1017/S1478951523000111. |
| 31818281 | Derived | Garrouste-Orgeas M, Flahault C, Poulain E, Evin A, Guirimand F, Fossez-Diaz V, Perruchio S, Verlaine C, Vanbesien A, Kaczmarek W, Birkui de Francqueville L, De Lariviere E, Bouquet G, Copel L, Verliac V, Marche V, Mathias C, Gracia D, Mhalla A, Michonneau-Gandon V, Poupardin C, Touzet L, Ranchou G, Guastella V, Richard B, Bienfait F, Sonrier M, Michel D, Ruckly S, Bailly S, Timsit JF. The Fami-life study: protocol of a prospective observational multicenter mixed study of psychological consequences of grieving relatives in French palliative care units on behalf of the family research in palliative care (F.R.I.P.C research network). BMC Palliat Care. 2019 Dec 9;18(1):111. doi: 10.1186/s12904-019-0496-4. |