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Study aims to prospectively evaluate if the pressures normally applied during mechanical ventilation in laparoscopic surgery induce stress on the pulmonary wall. To do this is used measure the variation of esophageal pressure, as indirect index of the pleural pressure and therefore of the transpulmonary pressure, in response to changes in airway pressures in a group of patients undergoing robotic assisted radical prostatectomy or videolaparoscopy.
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| Measure | Description | Time Frame |
|---|---|---|
| Incidence of postoperative acute complications | Evaluation of pulmonary alterations using pre and postoperative ultrasonographic visualization | 24 hours |
| Dosage of inflammatory mediators | Dosage of metalloproteinase and interleukin 8 in bronchoaspiration | 24 hours |
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Inclusion Criteria:
Exclusion Criteria:
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Patients underwent laparoscopic or robotic assisted radical prostatectomy
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Ester Forastiere, chief | Contact | ester.forastiere@ifo.gov.it |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Regina Elena National Cancer Institute | Recruiting | Rome | Rm | 00153 | Italy |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 39106592 | Derived | Covotta M, Claroni C, Torregiani G, Menga LS, Venti E, Gazze G, Anzellotti GM, Ceccarelli V, Gaglioti P, Orlando S, Rosa T, Forastiere E, Antonelli M, Grieco DL. Recruitment-to-inflation ratio to assess response to PEEP during laparoscopic surgery: A physiologic study. J Clin Anesth. 2024 Nov;98:111569. doi: 10.1016/j.jclinane.2024.111569. Epub 2024 Aug 5. |
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| ID | Term |
|---|---|
| D055397 | Ventilator-Induced Lung Injury |
| ID | Term |
|---|---|
| D055370 | Lung Injury |
| D008171 | Lung Diseases |
| D012140 | Respiratory Tract Diseases |
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| Regina Elena National Cancer Institute | Recruiting | Rome | 00154 | Italy |
|