A PHASE 2B/3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF PF-06651600 IN ADULT AND ADOLESCENT ALOPECIA AREATA (AA) SUBJECTS WITH 50% OR GREATER SCALP HAIR LOSS
A PHASE 2B/3 RANDOMIZED, DOUBLE-BLIND, PLACEBO-CONTROLLED, DOSE-RANGING STUDY TO INVESTIGATE THE EFFICACY AND SAFETY OF PF-06651600 IN ADULT AND ADOLESCENT ALOPECIA AREATA (AA) SUBJECTS WITH 50% OR GREATER SCALP HAIR LOSS
This is a global Phase 2b/3 study to evaluate the safety and effectiveness of an investigational study drug (called PF-06651600) in adults and adolescents (12 years and older) who have 50% or greater scalp hair loss. The study is placebo-controlled, meaning that some patients entering the study will not receive active study drug but will receive tablets with no active ingredients (a placebo). This is a dose-ranging study, investigating 5 different dosing regimens. It will be double-blinded, meaning that the sponsor, the study doctors, the staff, and the patients will not know whether a patient is on active study drug (or the dose) or placebo.
Inclusion Criteria:
Exclusion Criteria:
Birmingham, Alabama 35233, United States
Birmingham, Alabama 35233, United States
Birmingham, Alabama 35294, United States
Irvine, California 92697, United States
Aurora, Colorado 80045, United States
Washington D.C., District of Columbia 20007, United States
Washington D.C., District of Columbia 20010, United States
Washington D.C., District of Columbia 20016, United States
Chicago, Illinois 60611, United States
Iowa City, Iowa 52242, United States
Chevy Chase, Maryland 20815, United States
Minneapolis, Minnesota 55455, United States
New York, New York 10016, United States
CABA, Buenos Aires C1027AAP, Argentina
CABA, C1425DKG, Argentina
Wuhan, Hubei 430022, China
Shanghai, Shanghai Municipality 200040, China
Hangzhou, Zhejiang 310003, China
Hangzhou, Zhejiang 310009, China
Shanghai, 200025, China
Bogotá, D.C. 110221, Colombia
Praha 8- Liben, 180 81, Czechia
Koto-ku, Tokyo 136-0075, Japan
Shinjuku-ku, Tokyo 160-0023, Japan
Chelyabinsk, 454092, Russia
Moscow, 119991, Russia
Rostov-on-Don, 344002, Russia
Saint Petersburg, 191123, Russia
Saint Petersburg, 194021, Russia
Yaroslavl, 150003, Russia
New Taipei City, 23561, Taiwan
Southampton, Hampshire SO14 0YG, United Kingdom
Hampshire, SO16 6YD, United Kingdom
London, SE1 7EH, United Kingdom