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| Name | Class |
|---|---|
| Dongguan People's Hospital | OTHER_GOV |
| First People's Hospital, Shunde China | OTHER |
| Guangzhou Panyu Central Hospital | OTHER |
| Maoming People's Hospital |
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Few studies have attempt to improve DAPT adherence through social media. The investigators will explore the prevalence of DAPT discontinuation and prove the hypothesis that using social media will improve DAPT adherence among patients requiring DAPT following DES implantation.
Dual antiplatelet therapy (DAPT) is frequently discontinued after drug-eluting stent (DES) implantation, which could lead to many major adverse cardiovascular events (MACEs). Social media have been proven effective in improving lifestyles and blood pressures control, but few studies have attempt to improve DAPT adherence through social media.Therefore, eligible patients will be enrolled through scanning QR code and randomized in a 1:1 ratio to an intervention group or control group with 12 months of follow-up.The investigators will find out the prevalence of DAPT discontinuation and prove the hypothesis that using social media will improve DAPT adherence among patients requiring DAPT following DES implantation..
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Intervention Group | Experimental | The intervention group will receive usual text messages, personalized reminders and interactive responses. |
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| Control Group | Other | The control group will receive usual text messages only. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Usual Text Messages | Behavioral | Usual text messages four times a week, including cardiovascular knowledge and follow-up reminders, such as risk factors for CHD and typical symptoms of myocardial infarction. |
| Measure | Description | Time Frame |
|---|---|---|
| Rate of Discontinuation of Dual Antiplatelet Drug | Defined as discontinuation of any dual antiplatelet drug owing to patients' own discretion, including bleeding or non-compliance rather than doctors' advice. Changing of DAPT medication between ticagrelor and clopidogrel under doctors' advice will not be identified as dual antiplatelet drug discontinuation; changing of such under own discretion will be identified as such | 1 year |
| Measure | Description | Time Frame |
|---|---|---|
| Medication Adherence | Dual antiplatelet therapy (DAPT) adherence according to proportion of days covered (PDC) by prescription. | 1 year |
| Number of Participants with Major Adverse Cardiovascular Events |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Yong Liu, MD | Contact | 86-15920172292 | liuyong2099@126.com |
| Name | Affiliation | Role |
|---|---|---|
| Yong Liu, MD | Guangdong Cardiovascular Institute,Guangdong General Hospital | Study Chair |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Guangdong General Hospital | Recruiting | Guangzhou | Guangdong | 510080 | China |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31915170 | Derived | Sun GL, Lei L, Liu L, Liu J, He Y, Guo Z, Dai X, He L, Chen SQ, Liang Y, Ye J, Hu Y, Chen G, Chen JY, Liu Y. Rationale and design of the Web-basEd soCial media tecHnology to improvement in Adherence to dual anTiplatelet Therapy following Drug-Eluting Stent Implantation (WECHAT): protocol for a randomised controlled study. BMJ Open. 2020 Jan 7;10(1):e033017. doi: 10.1136/bmjopen-2019-033017. |
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| OTHER |
Randomization will be performed using a centralized, computerized randomization program in a uniform 1:1 allocation ratio.
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The patients (but not their care providers), research personnel, and investigators will be unaware of their allocation. Study coordinators and research assistants conducting the assessments and statisticians will also be blinded.
| Personalized Reminders | Behavioral |
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| Interactive Responses | Behavioral |
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All-cause mortality,target vessel revascularization, non-fatal myocardial infarction, and stroke
| 1 year |
| ID | Term |
|---|---|
| D003327 | Coronary Disease |
| ID | Term |
|---|---|
| D017202 | Myocardial Ischemia |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
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