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This study is aimed to understand the clinical characteristics, etiology and resistance phenotype of major pathogens of SCAP in China through multicenter and prospective investigation. Thus to provide epidemiological basis for improving the SCAP diagnosis and treatment protocol suitable for China.
During the study period, all patients who are diagnosed with SCAP and meet the inclusion criteria in the participating unit should be enrolled in the study . At the end of the trial, each participating unit should complete at least 20 qualified cases, and all participating units should have a total of more than 300 qualified cases.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| SCAP groups | all the SCAP patients who meet the inclusion criteria |
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| Measure | Description | Time Frame |
|---|---|---|
| Microbiological profile of lower respiratory tract specimens | Record the microbiological profile of lower respiratory tract specimens, including sputum, nasopharyngeal swabs, tracheobronchial aspirates and BAL fluid. | Day 0 of the study |
| Microbiological profile of urine specimens | Record the microbiological profile of urine specimens, including all the bacteria explored,especially legionella or streptoccus pneumonia. | Day 0 of the study |
| Microbiological profile of serum specimens | Record the microbiological profile of serum specimens , including all the bacteria explored, especially legionella, mycoplasma, chlamydia. | Day 0,14 days or 21 days of the study |
| Measure | Description | Time Frame |
|---|---|---|
| General conditions of the participants | Record the general conditions of the participants when included in the study ,such as demographic , clinical symptoms and signs of the participants, legionella contact history , enrollment date, ICU admitted condition, comorbidities, prior antibiotic treatment and so on. | Day 0 of the study |
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Inclusion Criteria:
Exclusion Criteria:
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SCAP patients who meet the inclusion criteria in China
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Jieming QU, Ph.D., M.D. | Contact | 0086-021-64370045 | jmqu0906@163.com | |
| Jing ZHANG, h.D.,M.D. | Contact | 0086-13472782754 | jingatlas@hotmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Jieming QU, h.D.,M.D. | Ruijin Hospital | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ruijin Hospital Shanghai Jiao Tong University School of Medicine | Recruiting | Shanghai | Shanghai Municipality | 200025 | China |
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| ID | Term |
|---|---|
| D000098968 | Community-Acquired Pneumonia |
| ID | Term |
|---|---|
| D017714 | Community-Acquired Infections |
| D007239 | Infections |
| D011014 | Pneumonia |
| D012141 | Respiratory Tract Infections |
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| Inflammatory Parameters |
Record the levels of WBC, CRP, PCT of the participants. |
| Day 0, 3 days of the study, and until the end of the study(approximately 1 year). |
| Arterial Blood Gas analysis of the participants | Record the arterial Blood Gas analysis(pH,PO2,PCO2 etc.) when included in the study. | Day 0 of the study |
| Chest Image of the participants | Record the chest radiograph of the participants when included in the study. | Day 0 of the study |
| Pneumonia Severity Index of the participants | Record the pneumonia severity index of the participants according to the PSI scoring system,which has been used to decide whether patients with pneumonia can be treated as outpatients or as (hospitalized) inpatients. | Day 0 of the study |
| CURB-65 Score of the participants | Assessment of consciousness, urea, respiratory rate, BP, and age 65 years score of the participants(Confusion-1,BUN>7mmol/l-1,Respiratory rate≥30-1,SBP<90mmHg,DBP≤60mmHg-1,Age≥65-1).The risk of death at 30 days increases as the score increases:0-0.6%,1-2.7%,2-6.8%,3-14.0%,4-27.8%,5-27.8%. | Day 0 of the study |
| Prognosis of the SCAP participants | Record the prognosis(cure,improvement,invalid,recrudesce,death) of the participants through the study completion. | up to 3 days of the study and until the end of the study(approximately 1 year). |
| D012140 |
| Respiratory Tract Diseases |