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This is a single centre、single arm、open-label,to investigate the safety and efficacy of induction of neural stem cells transplantation in the brain
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| iNSC treatment group | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Induction of neural stem cells | Biological | Brain injection iNSC |
|
| Measure | Description | Time Frame |
|---|---|---|
| Incidence of Treatment Emergent AE | 1 year |
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Inclusion Criteria:
Exclusion Criteria:
Any disabling psychological or psychiatric disorders which may confound the study.
History of more than one hemorrhagic stroke.
History of another major neurological disease or injury.
Cerebral soften lesion size >5cm in any one measurement.
Myocardial infarction within the prior 3 months.
History of seizures or current use of antiepileptic medication.
History of peripheral nerve surgery, including Selective Dorsal Rhizotomy and Contralateral Seventh Cervical Nerve Transfer.
Receipt of any investigational drug or device within 30 days.
Receipt of any cell infusion other than blood transfusion.
Any concomitant medical disease or condition noted below:
Any condition that the Investigator or primary physician feels may interfere with participation in the study or may endanger the subject.
Any condition that the surgeon feels may pose complications for the surgery.
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| ID | Term |
|---|---|
| D000083242 | Ischemic Stroke |
| ID | Term |
|---|---|
| D020521 | Stroke |
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
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| D009422 |
| Nervous System Diseases |
| D014652 | Vascular Diseases |
| D002318 | Cardiovascular Diseases |