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| ID | Type | Description | Link |
|---|---|---|---|
| A176000 | Other Identifier | UW Madison | |
| EDUC/KINESIOLOGY | Other Identifier | UW Madison | |
| Protocol Version 10/23/2018 | Other Identifier | UW Madison |
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Cerebrovascular function and peripheral vascular function will be measured in healthy young adults, before and after acute bouts of aerobic exercise at various intensities.
Acute bouts of aerobic exercise have been shown to enhance vascular reactivity of the peripheral circulation; however, the effects of a single exercise session on the cerebral circulation are unknown. This study will measure cerebrovascular function and peripheral vascular function before and after aerobic exercise at high and low intensities.
The research aims are:
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Aerobic Exercise | Other | Control: Cerebrovascular function and peripheral vascular function will be measured. Aerobic Exercise: Across four separate visits, participants will perform light intensity exercise, light intensity exercise plus an additional task, vigorous intensity exercise and vigorous intensity exercise to match the energy expenditure of light intensity exercise visit. |
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Control | Other |
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| Measure | Description | Time Frame |
|---|---|---|
| Cerebrovascular function | Utilize ultrasound to measure a change in blood flow velocity in response to a breathing test | Change in cerebrovascular function: measurements occur at baseline and 90 minutes post aerobic exercise to quantify magnitude of change. |
| Peripheral vascular function | Utilize ultrasound to measure a change in brachial artery diameter in response to reactive hyperemia | Change in peripheral vascular function: measurements occur at baseline and 60 minutes post aerobic exercise to quantify magnitude of change. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Gymnasium-Natatorium | Madison | Wisconsin | 53706 | United States |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 22442028 | Background | Barnes JN, Schmidt JE, Nicholson WT, Joyner MJ. Cyclooxygenase inhibition abolishes age-related differences in cerebral vasodilator responses to hypercapnia. J Appl Physiol (1985). 2012 Jun;112(11):1884-90. doi: 10.1152/japplphysiol.01270.2011. Epub 2012 Mar 22. | |
| 25146454 | Background | Richiardi J, Monsch AU, Haas T, Barkhof F, Van de Ville D, Radu EW, Kressig RW, Haller S. Altered cerebrovascular reactivity velocity in mild cognitive impairment and Alzheimer's disease. Neurobiol Aging. 2015 Jan;36(1):33-41. doi: 10.1016/j.neurobiolaging.2014.07.020. Epub 2014 Jul 24. |
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| ID | Term |
|---|---|
| D009043 | Motor Activity |
| ID | Term |
|---|---|
| D001519 | Behavior |
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| ID | Term |
|---|---|
| D015444 | Exercise |
| ID | Term |
|---|---|
| D009043 | Motor Activity |
| D009068 | Movement |
| D009142 | Musculoskeletal Physiological Phenomena |
| D055687 | Musculoskeletal and Neural Physiological Phenomena |
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| Aerobic Exercise |
| Other |
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