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| Name | Class |
|---|---|
| La Clinique des Maladies Infectieuses, Centre Hospitalier National Universitaire de Fann | UNKNOWN |
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Food insecurity can contribute to poor adherence to both tuberculosis treatment and antiretroviral therapy (ART). Interventions that target food insecurity have the potential to improve treatment adherence and decrease mortality. The goals of this study were to determine the cost, feasibility, acceptability, and potential impact of implementing nutritional support to improve adherence and treatment completion among HIV-TB co-infected adults in the Casamance region of Senegal, West Africa.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Food basket | Experimental |
| |
| Ready-to-Use Therapeutic Food | Experimental |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Food basket | Dietary Supplement |
| ||
| Ready-to-Use Therapeutic Food |
| Measure | Description | Time Frame |
|---|---|---|
| Uptake, as determined by percent of monthly nutritional support rations received, transported, stored, and utilized by subjects. | 6 months | |
| Acceptability, as determined by patient reported perceptions of nutritional support. | 6 months | |
| Costs of monthly nutritional support rations. | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Tuberculosis treatment adherence as determined by Medication Possession Ratio | 6 months | |
| Tuberculosis treatment adherence as determined by patient reported number of missed doses in the previous 7 days and 4 weeks. | 6 months |
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Inclusion Criteria:
Exclusion Criteria:
• Unwilling or unable to provide written informed consent
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| Name | Affiliation | Role |
|---|---|---|
| Noelle A Benzekri, MD | University of Washington | Principal Investigator |
| Moussa Seydi, MD | La Clinique des Maladies Infectieuses, CHNU de Fann | Principal Investigator |
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| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 31318879 | Derived | Benzekri NA, Sambou JF, Tamba IT, Diatta JP, Sall I, Cisse O, Thiam M, Bassene G, Badji NM, Faye K, Sall F, Malomar JJ, Seydi M, Gottlieb GS. Nutrition support for HIV-TB co-infected adults in Senegal, West Africa: A randomized pilot implementation study. PLoS One. 2019 Jul 18;14(7):e0219118. doi: 10.1371/journal.pone.0219118. eCollection 2019. |
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|
| Tuberculosis treatment completion defined as completing full course of prescribed therapy | 6 months |
| Adherence to antiretroviral therapy as determined by Medication Possession Ratio | 6 months |
| Adherence to antiretroviral therapy as determined by patient reported number of missed doses in the previous 7 days and 4 weeks | 6 months |
| CD4 cell count | 6 months |
| Presence of acid fast bacteria using sputum smear microscopy | 6 months |
| Results of GeneXpert | 6 months |
| Nutritional status as determined by Body Mass Index | 6 months |
| Nutritional status as determined by change in weight (kg) | 6 months |
| Food security status measured using the Household Food Insecurity Access Scale (HFIAS) | The HFIAS is a 9-item questionnaire which provides a household food insecurity score on a scale of 1-4, with 1 being not food insecure, 2 being mildly food insecure, 3 being moderately food insecure, and 4 being severely food insecure. | 6 months |
| Hemoglobin levels (g/dl) | 6 months |