Single Nucleotide Polymorphisms (SNPs) Associated With Postherpetic Neuralgia

Association Between Some Candidate Single Nucleotide Polymorphisms and Postherpetic Neuralgia

Postherpetic neuralgia (PHN) is a common condition and affecting 5 to 30% of the herpes zoster patients. In some cases, the pain remained refractory after first and second line treatment for herpes zoster. This suggests that there may be genetic variants that make some patients susceptible to PHN. Using saliva samples from herpes zoster patients the investigators are going to analyze the relationship between single nucleotide polymorphisms (SNPs) in genes that are known to be involved in pain and PHN.

Inclusion Criteria:

• Age more than 50 years
• Clinically defined herpes zoster patients

Exclusion Criteria:

• Patients not able to provide informed consent