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Robot-assisted laparoscopic radical prostatectomy (RALRP) is a surgical technique for the treatment of prostate cancer. The aim of this study was to report our initial experience with RALRP, by applying the concept of pentafecta. Pentafecta consists of the five main outcomes in the postoperative period of RALRP: erectile dysfunction, urinary incontinence, postoperative complications, surgical margins and biochemical failure.
This study will describe a initial experience in RALRP in Brazilian University Hospital. The follow-up of patients was performed as an examination at the medical consultation every three months. Complications were categorized according to the Clavien classification system. Biochemical failure was established by PSA level. Continence was defined as patients who remain dry and who do not require any kind of protection in their everyday activities. Sexual potency was defined as the ability to get and keep an erection for long enough to have satisfying sexual relations with or without the use of type-5 phosphodiesterase inhibitors (PDE-5) and a Sexual Health Inventory for Men (SHIM) score greater or equal to 21. Positive surgical margin is defined as the presence of neoplastic glands in direct contact with the ink on the surface of the piece, with no interposed connective tissue.
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| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Robot-assisted laparoscopic radical prostatectomy | Procedure | Patients with localized prostate cancer underwent transperitoneal robot-assisted laparoscopic radical prostatectomy |
| Measure | Description | Time Frame |
|---|---|---|
| Erectile Dysfunction | Sexual Health Inventory for Men (SHIM) score greater or equal to 21. | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Urinary Continence | Continence was defined as patients who remain dry and who do not require any kind of protection.Patients will be questioned in the postoperative consultations if there is a need to use some protection. | 6 months |
| Surgical Complication |
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Inclusion Criteria:
• patients diagnosed with localized Prostate Adenocarcinoma submitted to surgical treatment with Robot-assisted laparoscopic radical prostatectomy
Exclusion Criteria:
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Patients between 40 and 75 diagnosed with localized prostate cancer submitted to robot-assisted laparoscopic radical prostatectomy.
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Brasil S Neto, PhD | Contact | +55 51 33598286 | bneto@hcpa.edu.br | |
| Eduardo T Cachoeira, MD | Contact | +55 51 998123454 | cachoeira.uro@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Brasil S Neto, PhD | Hospital de Clinicas de Porto Alegre | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Hospital de Clinicas de Porto Alegre | Recruiting | Porto Alegre | Rio Grande do Sul | 90035 007 | Brazil |
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| ID | Term |
|---|---|
| D011471 | Prostatic Neoplasms |
| D007172 | Erectile Dysfunction |
| D014549 | Urinary Incontinence |
| D000072662 | Margins of Excision |
| ID | Term |
|---|---|
| D005834 | Genital Neoplasms, Male |
| D014565 | Urogenital Neoplasms |
| D009371 | Neoplasms by Site |
| D009369 | Neoplasms |
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Complications were categorized according to the Clavien classification system. |
| 30 days |
| Biochemical Failure | Biochemical failure was established by PSA level grater or equal to 0,2 ng/ml. | 6 month |
| Surgical Margin | It is defined as the presence of neoplastic glands in direct contact with the ink on the surface of the piece. | 15 days |
| D005832 |
| Genital Diseases, Male |
| D000091662 | Genital Diseases |
| D000091642 | Urogenital Diseases |
| D011469 | Prostatic Diseases |
| D052801 | Male Urogenital Diseases |
| D012735 | Sexual Dysfunction, Physiological |
| D020018 | Sexual Dysfunctions, Psychological |
| D001523 | Mental Disorders |
| D014555 | Urination Disorders |
| D014570 | Urologic Diseases |
| D052776 | Female Urogenital Diseases |
| D005261 | Female Urogenital Diseases and Pregnancy Complications |
| D059411 | Lower Urinary Tract Symptoms |
| D020924 | Urological Manifestations |
| D012816 | Signs and Symptoms |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D065308 | Morphological and Microscopic Findings |