A Study to evaluate the efficacy of psychotherapy for easing the cardiac symptoms and improving and quality of life in patients with hypertrophic cardiomyopathy accompanied with depression

This study will use a 8 week parallel group design. 100 patients diagnosed as hypertrophic cardiomyopathy accompanied with depression will be into experimental group and control group. The experimental group received 8 times of psychological treatments for once each week; the control group did not receive any antidepressant treatment. Follow-up assessments will be performed at baseline, week 4 and 8.

Inclusion Criteria:

• Diagnosed as hypertrophic cardiomyopathy;
• Diagnosed as depression;

Exclusion Criteria:

• Patients with left ventricular ejection fraction (EF) ≦ 30%;
• Renal dysfunction with serum creatinine ≧451umol/l;
• Severe heart failure and New York Heart Association (NYHA) Heart Failure Grade III;
• Combine with any type of malignant tumor;
• Combine with other serious mental illnesses such as bipolar disorder, schizophrenia, schizophrenia-like illness, severe dementia, etc.;
• Have received medication of antidepressant or psychotherapy;
• Patients with major depression; Patients with a serious risk of suicide or have had suicide attempts;
• Pregnant women and lactating women, or women who are planning to become pregnant or breastfeeding during the study period;
• Other circumstances in which the researcher judges that it is not suitable as a research object.

The investigator have not decided whether or not to share the data.