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The aim of this study was to determine whether changes in serum levels of syndecan-1 before and after surgery, which is an index related to injury of the endothelial glycocalyx layer, are associated with postoperative short-term complications and mortality in patients undergoing robotic esophagectomy.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| patients undergoing robotic esophagectomy | Patients 20 years or older who undergo robotic esophagectomy |
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| Measure | Description | Time Frame |
|---|---|---|
| base blood concentration of syndecan-1 | preoperative baseline serum levels of syndecan-1 | within 1 hour before surgery |
| blood concentration of syndecan-1 at the end of the surgery | blood concentration of syndecan-1 at the end of the surgery | within 5 minutes after the end of surgery (when thd surgical drape is removed) |
| blood concentration of syndecan-1 at 24 hours after surgery | blood concentration of syndecan-1 at 24 hours after surgery | 24 hours after the end of surgery |
| Measure | Description | Time Frame |
|---|---|---|
| Unanticipated Post-Operative Invasive Procedure (STS GTSD 2.41 #3330) | Indicate if the patient had an unplanned invasive procedure after surgery. Examples includes return to the operating room for a redo surgical procedure, a percutaneous procedure performed at bedside or in the radiology suite, a tracheostomy, and wound opening at bedside. Exclusions: postoperative toilet bronchoscopy, central venous access, arterial line placement, foley catheter placement. |
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Inclusion Criteria:
1. patients 20 years or older who undergo robotic esophagectomy
Exclusion Criteria:
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patients 20 years or older who undergo robotic esophagectomy
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Anesthesiology and Pain Medicine, Yonsei University College of Medicine | Seoul | 03722 | South Korea |
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| during this 1 day hospital visit. |
| Anastomotic leak following esophageal surgery(STS GTSD 2.41 #3350) | Indicate if the patient had an anastomotic leak following esophageal surgery. | within 30days after end of surgery |
| Respiratory Failure(STS GTSD 2.41 #3480) | Indicate whether the patient experienced respiratory failure in the postoperative period requiring mechanical ventilation and/or reintubation. | within 30days after end of surgery |
| initial ventilatory support greater than 48 hours (STS GTSD 2.41 #3520) | Indicate if the patient initially was ventilated greater than 48 hours in the postoperative period. If the patient is reintubated, select the postoperative event "Respiratory Failure" and do not select this element even if the reintubation ventilator support is > 48 hours. Ventilator support ends with the removal of the endotracheal tube or if the patient has a tracheostomy tube, until no longer ventilator dependent. | within 30days after end of surgery |
| pneumonia (STS GTSD 2.41 #3460) | Indicate if the patient experienced pneumonia in the postoperative period. Pneumonia is defined as meeting three of five characteristics: fever (> 100.4 F or 38 C), leukocytosis, CXR with infiltrate, positive culture from sputum, or treatment with antibiotics. | within 30days after end of surgery |
| renal failure(STS GTSD 2.41 #3810) | Indicate whether the patient had acute renal failure or worsening renal function resulting in any of the following:
| within 30days after end of surgery |
| mortality(Status 30 Days after Surgery, STS GTSD 2.41 #3950) | Indicate whether the patient was alive or dead at 30 days post-surgery (whether in the hospital or not). time frame: 30days post-surgery | 30days post-surgery |
| Acute kidney injury | defined as an absolute increase in serum creatinine level C0.3 mg/dL, a 50% (1.5-fold) increase in serum creatinine level from baseline, or a reduction in urine output (documented oliguria< 0.5 mL/kg/h for 6h) | within 48 h after end of surgery |