The goal of the study is to understand the treatment patterns for immunotherapy agents and BRAF/MEK inhibitors used in the treatment of advanced melanoma

Inclusion Criteria:

• Patients must have ≥1 medical or pharmacy claim for nivolumab, ipilimumab, pembrolizumab, nivolumab+ipilimumab (on the same day), dabrafenib, vemurafenib, cobimetinib, trametinib, dabrafenib+trametinib (on the same day) and vemurafenib+cobimetinib (on the same day)
• Patients must have ≥6 months of continuous health plan enrollment prior to index date
• Patients must have ≥2 medical claims at least 30 days apart with a diagnosis for melanoma during the study period AND ≥1 diagnosis for melanoma during the baseline period prior to or on the index date

Exclusion Criteria:

• Patients with ≥1 claim for the agents of interest including immunotherapy agents and BRAF/MEK inhibitors between the first diagnosis of metastatic disease and the day prior to the index date will be excluded
• Patients with a claim for acquired immunodeficiency virus (AIDS) anytime during the study period
• Patients under the age of 18 as of index date

Other protocol defined inclusion/exclusion criteria could apply

Patients with advanced melanoma treated with immunotherapy and BRAF/MEK inhibitors