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patients with Miller class I , II gingival recession will be divided into 2 groups (control, intervention).the control one will receive coronally advanced flap with subepithililal connective tissue graft harvested from the palate while the intervention one will have coronally advanced flap with advanced platelet rich fibrin(A-PRF).as it represent a new generation of platelet concentrate allow for better healing and root coverage results.
Null hypothesis: In patients with Miller class I and II gingival recession, there is no difference in amount of root coverage (mm) following the application of SCTG+A-PRF compared to CAF+SCTG.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| intervention | Active Comparator | CAF+ APRF |
|
| control | Active Comparator | CAF+SCTG |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| CAF + (A-PRF) | Procedure | advanced platelet rich fibrin prepared by low speed centrfugation concept(LSCC) together with coronally advanced flap . |
|
| Measure | Description | Time Frame |
|---|---|---|
| root coverage | measured in millimeter | 9 months |
| Measure | Description | Time Frame |
|---|---|---|
| Gingival esthetics | Root coverage esthetic score | 9 months |
| Recession width | measured in millimeter | 9 months |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| heba samir mahmoud, assistant lecturer | Contact | 01222541606 | heba227@gmail.com |
| Name | Affiliation | Role |
|---|---|---|
| Heba Samir Mhmoud, assistant lecturer | Cairo University | Principal Investigator |
| Manal M Hosny, professor | Cairo University | Study Director |
| Engi A Mahmoud, assistant professor |
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| CAF+SCTG | Procedure | cornally advanced flap plus subepithilial connective tissue graft harvested from the palate |
|
| Clinical attachment level | measured in millimeter | 9 months |
| Width of keratinized gingiva | measured in millimeter | 9 months |
| Probing depth | measured in millimeter | 9 months |
| Gingival thickness | measured in millimeter | 9 months |
| Post-operative pain | Visual analog scale (VAS) Questionnaire | measured daily for the first 2 weeks post- operatively. |
| Patient Satisfaction | Post-Surgical Patient Satisfaction Questionnaire | 9 months |
| Early wound healing | Early wound healing index | 1,2,4 weeks post- surgical |
| Cairo University |
| Study Chair |
| ID | Term |
|---|---|
| D005889 | Gingival Recession |
| ID | Term |
|---|---|
| D005882 | Gingival Diseases |
| D010510 | Periodontal Diseases |
| D009059 | Mouth Diseases |
| D009057 | Stomatognathic Diseases |
| D055093 | Periodontal Atrophy |
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