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| Name | Class |
|---|---|
| Aikaterini Kalampokini | UNKNOWN |
| Chryssoula Staikou | UNKNOWN |
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100 patients ASA I-III, undergoing total knee arthroplasty under spinal anesthesia, will be randomly assigned into one of two groups, namely group A (n=50), where an adductor canal block and an IPACK block will be performed preoperatively and group B (n=50) where an adductor canal block only will be performed preoperatively. All patients will receive a standardized multimodal approach, including pregabalin, paracetamol, and PCA with morphine. NRS scores in static and dynamic conditions during the first 48 hours postoperatively, morphine consumption during the first 24 hours postoperatively will be measured and additionally, patient satisfaction, complications, range of knee motion, moblization, functionality, delirium ocurence will be recorded. Chronic pain will be assessed in 3 and 6 months postoperatively.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group A | Active Comparator |
| |
| Group B | Active Comparator |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Adductor Canal Block plus IPACK Block | Drug | Adductor Canal Block plus IPACK Block using Ropivacaine |
|
| Measure | Description | Time Frame |
|---|---|---|
| NRS scores | Numerical Rating Scale (NRS) scores (Range 0-10, 0=no pain, 10=the worse pain ever) | 48 hours |
| Morphine consumption | Morphine consumption in mg | 24 hours |
| Chronic pain | Using of Graded Chronic Pain Scale (GCPS) Grade 0: No pain in prior 6 months Grade 1: Low Intensity - Low Disability Grade II: High Intensity Characteristic Pain Intensity - Low Disability Grade III: High Disability - Moderately Limiting Grade IV: High Disability - Severely Limiting | 6 months |
| Measure | Description | Time Frame |
|---|---|---|
| Delirium occurence | Nu-DESK scale (presence of disorientation, inappropriate behavior, inappropriate communication,illusions/hallucinations, psychomoter retardation). Each of the 5 items is rated from 0 to 2. A total of 10 is the maximum score. A score of more than 2 identifies the presence of delirium. | 48 hours |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Alexandros Makris | Contact | +306947076446 | makrisalexandros@hotmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Asklepieion Hospital of Voula | Recruiting | Athens | 16673 | Greece |
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| Adductor Canal Block | Drug | Adductor Canal Block using Ropivacaine |
|
| Range of knee motion |
Degrees of flexion |
| 48 hours |
| Complications | 48 hours |
| Patient mobilization | Patient reporting time of first standing to the side of the bed and number of steps per day | 5 days |
| Patient satisfaction | Patients asked whether they would choose the same anaesthetic management in a future operation: Yes/No | 48 hours |
| Joint function | Maximal flexion / extension | 6 months |
| Intestinal function | Time of first passing of rectal gas, reported by the patient | 5 days |