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To assess the Postoperative Pain after using Silver Nanoparticles with and without Calcium Hydroxide as an Intracanal Medication in Patients with necrotic pulp (RCT)
When the treatment itself appears to initiate the onset of pain and/or swelling, the result can be very distressing to both the patient and the operator. Patients might even consider postoperative pain and flare-up as a benchmark against which the clinician's skills are measured. Prevalence of postoperative pain or flare-up is, therefore, one of the influencing factors when making a clinical decision. Better management of postoperative pain increases the patients' confidence in dentist's skills and gives positive attitude toward dental profession. In cases with necrotic pulp, the incidence of pain becomes higher, hence testing which intracanal medication is more effective in decreasing the bacteria present within the root canal and subsequently pain is crucial.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| AgNP/Ca(OH) | Active Comparator | Patients receiving combined Silver nanoparticle/Calcium hydroxide administered as intracanal medication at the first visit after cleaning and shaping |
|
| AgNP | Active Comparator | Patients receiving silver nanoparticles in gel form administered as intracanal medication at the first visit after cleaning and shaping |
|
| Ca(OH) | Active Comparator | Patients receiving calcium hydroxide intracanal medication at the first visit after cleaning and shaping |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Silver nanoparticle/Calcium hydroxide | Combination Product | Intracanal Medication composed of combined silver nanoparticles with calcium hydroxide |
|
| Measure | Description | Time Frame |
|---|---|---|
| Change in post-operative pain | Numerical (0-10) | Intra-appointment and post obturation at 4, 24, 48, 72, 96 hours |
| Measure | Description | Time Frame |
|---|---|---|
| Intracanal Bacterial count reduction | Quantification of Colony forming units per milliliter of agar medium (CFU/mL) | 1 week |
| Number of analgesic tablets taken by the patient after endodontic treatment |
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Inclusion Criteria:
Exclusion Criteria:
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| Name | Affiliation | Role |
|---|---|---|
| Nermine Hassan, Msc | Cairo University | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Cairo University | Cairo | Manial | 11553 | Egypt |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 23657409 | Background | Singh RD, Khatter R, Bal RK, Bal CS. Intracanal medications versus placebo in reducing postoperative endodontic pain--a double-blind randomized clinical trial. Braz Dent J. 2013;24(1):25-9. doi: 10.1590/0103-6440201302039. |
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Participant data will be made available
It will be available after finishing the study
It will be uploaded on a folder on google drive to be accessed through this link
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| Silver Nanoparticles in gel form | Drug | Intracanal medication composed of silver nanoparticles in gel form |
|
| Calcium Hydroxide Intracanal medication | Drug | Calcium hydroxide intracanal medication |
|
Number
| Within 4 days after the first session and after 1 week from first treatment session |
| ID | Term |
|---|---|
| D010149 | Pain, Postoperative |
| ID | Term |
|---|---|
| D011183 | Postoperative Complications |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
| D010146 | Pain |
| D009461 | Neurologic Manifestations |
| D012816 | Signs and Symptoms |
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| ID | Term |
|---|---|
| D002126 | Calcium Hydroxide |
| C586932 | colloidal silver |
| ID | Term |
|---|---|
| D006878 | Hydroxides |
| D000468 | Alkalies |
| D007287 | Inorganic Chemicals |
| D017610 | Calcium Compounds |
| D000838 | Anions |
| D007477 | Ions |
| D004573 | Electrolytes |
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