This study aims at describing survival rates over time (Kaplan-Meier estimator) in patients suffering from AIDS-related primary central nervous system lymphoma who were diagnosed from 1996 to 2014 and treated with infusions of high-dose methotrexate and combined antiretroviral therapy.

Inclusion Criteria:

• HIV infection
• AIDS-related primary central nervous system lymphoma
• treated with at least one infusion of methotrexate and combine antiretroviral therapy

Exclusion Criteria:

• prior non-Hodgkin lymphoma

All patients treated for AIDS-related primary central nervous system lymphoma in Fondation Rothschild (Paris, France) between january1996 and december 2014