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The healthcare system in Sweden is publicly funded and aims to provide equal access to care irrespective of socioeconomic status. This includes ensuring equity in drug treatment. Socioeconomic disparities have been shown to influence patient management and health outcomes in certain Swedish populations. The Swedish Board of Health and Welfare has stated that the prescription of new drugs, which are more expensive than generic standard of care drugs, might be influenced by patients' socioeconomic status.
To evaluate the association between socioeconomic factors and use of a DOAC (rivaroxaban, dabigatran, or apixaban) or standard of care (warfarin) in patients with NVAF in Sweden.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| DOACs (Direct Oral Anticoagulants) |
| ||
| Standard of care |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| DOACs: Rivaroxaban, Dabigatran, Apixaban | Drug | Routinely collected clinical data (secondary data from patients with non-valvular atrial fibrillation in Sweden); no primary data collection |
| Measure | Description | Time Frame |
|---|---|---|
| Correlation between socioeconomic factors and use of DOACs vs. Warfarin (as identified from the LISA database before the index date) | Between 1 December 2011 and 31 December 2014; Socioeconomic factors:
| approximately 3 years |
| Measure | Description | Time Frame |
|---|---|---|
| Secular trends in the correlation between socioeconomic factors and use of DOACs (vs. warfarin) - Trends based on the date of prescription by year | Between 1 December 2011 and 31 December 2014; Relationship between socioeconomic factors and access to newly marketed drugs (DOACs as one class which includes Rivaroxaban, Dabigatran and Apixaban) versus standard of care (warfarin) for different calender period. |
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Inclusion Criteria:
Exclusion Criteria:
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Stockholm | Sweden |
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| ID | Term |
|---|---|
| D000069604 | Dabigatran |
| C522181 | apixaban |
| D059039 | Standard of Care |
| D014859 | Warfarin |
| ID | Term |
|---|---|
| D011725 | Pyridines |
| D006573 | Heterocyclic Compounds, 1-Ring |
| D006571 | Heterocyclic Compounds |
| D001562 | Benzimidazoles |
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| Standard of care (Warfarin) | Drug | Routinely collected clinical data (secondary data from patients with non-valvular atrial fibrillation in Sweden); no primary data collection |
|
| approximately 3 years |
| D006574 |
| Heterocyclic Compounds, 2-Ring |
| D000072471 | Heterocyclic Compounds, Fused-Ring |
| D019984 | Quality Indicators, Health Care |
| D011787 | Quality of Health Care |
| D006298 | Health Services Administration |
| D017530 | Health Care Quality, Access, and Evaluation |
| D015110 | 4-Hydroxycoumarins |
| D003374 | Coumarins |
| D001578 | Benzopyrans |
| D011714 | Pyrans |