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Different ventilation modes can be used in laparoscopic surgeries. These surgeries are performed in steep Trendelenburg position with serious hemodynamic disturbances. This study aims to observe the hemodynamic effects of two different ventilation modes in laparoscopic gynecologic surgery performed in steep Trendelenburg position.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Group V | The patients in this group are ventilated using VCV (Volume Control Ventilation) mode (FiO2 50%, Tidal volume: 6-8 ml/kg (ideal body weight), frequency: 12/minute, I/E ratio: 1/2, PEEP not applied) |
| |
| Group P | The patients in this group are ventilated using PCV-VG (Volume Guaranteed Pressure Control Ventilation) mode (FiO2 50%, Tidal volume: 6-8 ml/kg (ideal body weight), frequency: 12/minute (EtCO2 kept between 35-40 mmHg), Pressure limit: 30 cm H2O, I/E:1/2, PEEP not applied) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Mode of Mechanical Ventilation | Procedure | Adjustment of mechanical ventilation mode |
|
| Measure | Description | Time Frame |
|---|---|---|
| Measurement of changes in MAP | Mean arterial pressure (MAP) (mmHg) | T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Measurement of changes in heart rate | Heart rate (bpm) | T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Measurement of changes in systemic vascular resistance index | Systemic vascular resistance index (dyne x sec/cm2) | T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Measurement of changes in stroke volume index | Stroke volume index (mL/m2) | T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Measurement of changes in cardiac index | Cardiac index L(min x m2) | T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Measurement of changes in stroke volume variation | Stroke volume variation (%) | T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Measurement of changes in cardiac cycle efficiency | Cardiac cycle efficiency (units) |
| Measure | Description | Time Frame |
|---|---|---|
| Measurement of changes in peak airway pressure | Ppeak (Peak airway pressure) | T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Measurement of changes in mean airway pressure |
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Inclusion Criteria:
Exclusion Criteria:
Observations will be performed in laparoscopic gynecological operations
Women between 18 and 65 years of age scheduled to undergo elective gynecologic laparoscopic surgery
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Perihan Ekmekçi, MD | Contact | +903122044000 | 4424 | erdogduperi@gmail.com |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Ufuk University Faculty of Medicine | Recruiting | Ankara | Balgat | 06520 | Turkey (Türkiye) |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 18414959 | Background | Balderi T, Forfori F, Marra V, Di Salvo C, Dorigo M, Anselmino M, Romano SM, Giunta F. Continuous hemodynamic monitoring during laparoscopic gastric bypass in superobese patients by pressure recording analytical method. Obes Surg. 2008 Aug;18(8):1007-14. doi: 10.1007/s11695-007-9379-5. Epub 2008 Apr 15. | |
| 26772778 | Background |
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| Type | Date | Date Unknown |
|---|---|---|
| Release | Aug 19, 2020 | |
| Reset | Sep 8, 2020 |
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| Release Date | Unrelease Date | Unrelease Date Unknown | Reset Date | MCP Release Number |
|---|---|---|---|---|
| Aug 19, 2020 | Sep 8, 2020 |
| ID | Term |
|---|---|
| D053120 | Respiratory Aspiration |
| ID | Term |
|---|---|
| D012120 | Respiration Disorders |
| D012140 | Respiratory Tract Diseases |
| D010335 | Pathologic Processes |
| D013568 | Pathological Conditions, Signs and Symptoms |
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| T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Measurement of changes in aortic dp/dt | Aortic dP/dt (mmHg/msec) | T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
Pmean (Mean Airway Pressure),
| T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Measurement of changes in plateau airway pressure | Pplateau (Plateau Airway Pressure) | T0: Induction (Baseline) T1: Change after 30 minutes pneumoperitoneum T2: Change after desufflation |
| Liao CC, Kau YC, Ting PC, Tsai SC, Wang CJ. The Effects of Volume-Controlled and Pressure-Controlled Ventilation on Lung Mechanics, Oxidative Stress, and Recovery in Gynecologic Laparoscopic Surgery. J Minim Invasive Gynecol. 2016 Mar-Apr;23(3):410-7. doi: 10.1016/j.jmig.2015.12.015. Epub 2016 Jan 7. |