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Knee osteoarthritis is an important cause of functional disabilities at old age. Previous research has demonstrated that individuals with knee osteoarthritis have reduced knee-extensor strength in comparison to healthy individuals. However, rapid power production declines more than strength as a consequence of ageing and is more predictive of functional capacity. However, limited research has investigated whether individuals with knee osteoarthritis have reduced ability to develop strength and power rapidly on top of reduced maximal strength capacities, which is the primary aim of the current study.
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| Label | Type | Description | Intervention Names |
|---|---|---|---|
| Older adults with knee osteoarthritis (>50 years) |
| ||
| Healthy older adults (> 50 years) |
|
| Name | Type | Description | Arm Group Labels | Other Names |
|---|---|---|---|---|
| Muscle function test | Diagnostic Test | Power and strength tests of the knee-extensor muscles, handgrip strength, functional capacity tests |
|
| Measure | Description | Time Frame |
|---|---|---|
| Rate of power development | Subjects perform a test protocol on a Biodex dynamometer, consisting of isotonic contractions of the leg-extensor muscles. Subjects are instructed to kick as fast as possible against different (relative) loads. The rate of power development (watt/s) is defined as the linear slope of the power-time curve and is measured from the onset of movement till peak power. | up to 3 months |
| Measure | Description | Time Frame |
|---|---|---|
| Maximal isometric strength | Maximal strength (Nm) is measured by means of unilateral isometric knee-extensor tests on a Biodex dynamometer. | up to 3 months |
| Maximal isokinetic strength | Maximal strength (Nm) is measured by means of unilateral isokinetic knee-extensor tests on a Biodex dynamometer. |
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Inclusion Criteria:
Group with knee osteoarthritis:
- Diagnosed with knee osteoarthritis based on RX.
Exclusion Criteria:
Healthy group:
Group with knee osteoarthritis:
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Adults between 50 and 80 years with or without knee osteoarthritis. Subjects are sedentary or recreationally active.
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Department of Movement Sciences | Leuven | 3001 | Belgium |
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| ID | Term |
|---|---|
| D020370 | Osteoarthritis, Knee |
| ID | Term |
|---|---|
| D010003 | Osteoarthritis |
| D001168 | Arthritis |
| D007592 | Joint Diseases |
| D009140 | Musculoskeletal Diseases |
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| up to 3 months |
| Stair Climbing performance | Stair ascent duration (in s), the time needed to ascent a flight of stairs. | up to 3 months |
| Gait speed | The average speed to walk 10m as fast as possible (in m/s). | up to 3 months |
| 5 repetition sit-to-stand test | The time needed to perform 5 sit-to-stand transitions (in s). | up to 3 months |
| Timed-up-and-go | The time needed to stand up from a chair, walk 3m, turn, walk back and sit down. | up to 3 months |
| Handgrip strength | Handgrip strength (kg) evaluated with Jamar dynamometer. | up to 3 months |
| D012216 |
| Rheumatic Diseases |