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The aim of this study is to analyse the short-term results of the first patients undergoing the OZAKI procedure (Aortic valve reconstruction using autologous pericardial tissue) at the department of cardiac surgery/ University Hospital Basel/ Switzerland.
The reconstruction of the aortic valve using autologous pericardium, applying the technique Ozaki et al., published first in 2011 provides potential benefits due to the missing necessity of oral anticoagulation and its use in patients with small aortic annuli, because of the huge orifice area. There is a need of more data to evaluate the significance of this technique in the treatment of aortic valve stenosis and regurgitation. The department of cardiac surgery/ University Hospital Basel/ Switzerland started to use this technique in September 2015. The aim of this study is to analyse the short-term results of the first patients undergoing the OZAKI procedure.
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| Measure | Description | Time Frame |
|---|---|---|
| Change in aortic transvalvular gradient measured by transthoracic echocardiography | Change in aortic transvalvular gradient ( to analyze aortic valve stenosis or insufficiency) measured by transthoracic echocardiography | From Baseline (end of cardiac surgery) until 12 months after cardiac surgery |
| Measure | Description | Time Frame |
|---|---|---|
| occurence of death | Change in clinical Parameter: death | From Baseline (end of cardiac surgery) until 12 months after cardiac surgery |
| occurence of cardiac re-surgery | Change in clinical parameter: cardiac re-surgery |
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Inclusion Criteria:
Exclusion Criteria:
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Patients undergoing aortic valve reconstruction using autologous pericardium (OZAKI technique) in Universitätsspital Basel/ Switzerland since September 2015.
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| Name | Affiliation | Role |
|---|---|---|
| Oliver Reuthebuch, PD Dr. med | University Hospital, Basel, Switzerland | Principal Investigator |
| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Herzchirurgie University Hospital Basel | Basel | Canton of Basel-City | 4031 | Switzerland |
| PubMed Identifier | Type | Citation | Retractions |
|---|---|---|---|
| 32458022 | Derived | Koechlin L, Schurr U, Miazza J, Imhof S, Maurer M, Erb J, Gahl B, Santer D, Berdajs D, Eckstein FS, Reuthebuch O. Echocardiographic and Clinical Follow-up After Aortic Valve Neocuspidization Using Autologous Pericardium. World J Surg. 2020 Sep;44(9):3175-3181. doi: 10.1007/s00268-020-05588-x. |
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| ID | Term |
|---|---|
| D000082862 | Aortic Valve Disease |
| ID | Term |
|---|---|
| D006349 | Heart Valve Diseases |
| D006331 | Heart Diseases |
| D002318 | Cardiovascular Diseases |
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| From Baseline (end of cardiac surgery) until 12 months after cardiac surgery |
| occurence of stroke | Change in clinical parameter: stroke | From Baseline (end of cardiac surgery) until 12 months after cardiac surgery |