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The cerebral arteriovenous malformations correspond to the formation of an entanglement of morphologically abnormal vessels called nidus, which shunt the blood circulation directly from the arterial circulation to the venous circulation.
The cerebral arteriovenous malformations are an important cause of hemorrhagic stroke.
The hypothesis is that cerebral haemorrhage associated with a cerebral arteriovenous malformations would come from peri-nidal micro-vessels, in connection with infiltration of leucocytes and / or defective maintenance of microvascular integrity by platelets.
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| Measure | Description | Time Frame |
|---|---|---|
| Associaton between dosage of endothelial marker and the arteriovenous malformation pronostic | associaton between dosage of endothelial marker in blood samples and correlation with clinical outcome | 6 months |
| Associaton between dosage of platelet and the arteriovenous malformation pronostic | Dosage of platelet in blood samples and correlation with clinical outcome | 6 months |
| Associaton between dosage of neutrophilic and the arteriovenous malformation pronostic | Dosage of neutrophilic in blood samples and correlation with clinical outcome | 6 months |
| Associaton between neo-angiogenesis activation markers and the arteriovenous malformation pronostic | Dosage neo-angiogenesis activation markers in blood samples and correlation with clinical outcome | 6 months |
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Inclusion Criteria:
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Exclusion Criteria:
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Patient with a cerebral arterioveinus malformation for which an intervention (endovascular treatment or surgery) or only clinical monitoring is planned
| Name | Role | Phone | Extension | |
|---|---|---|---|---|
| Amélie Yavchitz | Contact | 01 48 63 64 54 | +33 | ayavchitz@for.paris |
| Jean Philippe DESILLES | Contact | jp.desilles@for.paris |
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| Facility | Status | City | State | ZIP | Country | Contacts |
|---|---|---|---|---|---|---|
| Fondation Ophtalmologique Rotschild | Recruiting | Paris | 75019 | France |
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| ID | Term |
|---|---|
| D002538 | Intracranial Arteriovenous Malformations |
| D012421 | Rupture |
| ID | Term |
|---|---|
| D002561 | Cerebrovascular Disorders |
| D001927 | Brain Diseases |
| D002493 | Central Nervous System Diseases |
| D009422 | Nervous System Diseases |
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| D020785 | Central Nervous System Vascular Malformations |
| D009421 | Nervous System Malformations |
| D001165 | Arteriovenous Malformations |
| D054079 | Vascular Malformations |
| D018376 | Cardiovascular Abnormalities |
| D002318 | Cardiovascular Diseases |
| D014652 | Vascular Diseases |
| D020765 | Intracranial Arterial Diseases |
| D000013 | Congenital Abnormalities |
| D009358 | Congenital, Hereditary, and Neonatal Diseases and Abnormalities |
| D014947 | Wounds and Injuries |