Impedancemetry in Patients Monitored for Pulmonary Hypertension

Prognostic Value of Cardiac Output Measured by Impedancemetry in Patients Monitored for Pulmonary Hypertension

Monocentric cohort study, prospective, evaluating the variability of cardiac output measurement by resting and stress impedancemetry as a prognostic factor for Pulmonary Hypertension

Cardiac impedancemetry is a technique that allows an electrical representation of cardiac flows. To do this, 6 electrodes are applied to the thorax and a low intensity and high frequency electrical current is transmitted. The impedance is recorded and the variations of the impedance represent the changes in intra-thoracic volume and thus the volume of systolic ejection. This measurement can be done at rest but also during exercise during the walking test. A test of the NO / CO coupled transfer measurement is also performed.

The devices that will be used in this project are the Physio-Flow® system and Masterscreen NO / CO coupled transfer measurement device

Inclusion Criteria:

• Patient over 18 years and under 80 years
• Patients who have been diagnosed with PAH (group 1 PH according to the Nice 2013 classification) or post-embolic pulmonary hypertension (group 4 PH) under medical treatment;
• HTP incident or prevalent less than 6 months
• Patient coming for follow-up or emergency consultation or hospitalization with a clinical examination and a walking test
• Patient affiliated to a health insurance scheme
• Patient having signed informed consent

Exclusion Criteria:

• Subjects under juridical protections or tutelage measure
• pregnant or lactating woman
• pulmonary hypertension du to cardiac pathology, chronic respiratory disease, or uncertain determinism.
• pulmonary hypertension of group 4 treated surgically or endoscopically.
• pulmonary hypertension incident or prevail for 6 months or more
• contraindication to impedancemetry
• inability to perform a walking test