This is a research study to compare the well-being (caregiver strain index) of caregivers of patients receiving home vs standard care after autologous hematopoietic stem cell transplant.

Patient Inclusion Criteria:

• Scheduled to undergo an autologous hematopoietic stem cell transplant for any cancer or non-cancer illness
• Age 18-80 years
• Karnofsky Performance Scale KPS> 80
• Able to read/write English
• A home that is deemed, upon inspection, in suitable condition to serve as a medical home, within a 90-minute driving distance of Duke

Patient Exclusion Criteria:

• Lack of a caregiver
• Pregnant women
• Patients with a documented active infection prior to starting their preparative regimen. This includes grade 3 or higher viral, bacterial, or fungal infection.
• Use of homeopathic medications, prebiotics, or probiotics that may impact gut microbiota

Caregiver Inclusion Criteria:

• Identified by patient as their primary caregiver
• Meet standard clinical criteria for being a caregiver (able to drive and take care of patient)
• Age 18-80 years

Caregiver Exclusion Criteria:

None